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Bevacimab 400400mg/16ml

Injection
rx_reqRequire Prescription
Healthcare Pharmaceuticals Ltd.
Generic: Bevacizumab
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descriptionSafety Advices
AlcoholAlcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Bevacimab 400. Please consult your doctor.
PregnancyPregnancy
CONSULT YOUR DOCTOR
Bevacimab 400 may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the deve... View More
BreastfeedingBreastfeeding
CONSULT YOUR DOCTOR
Bevacimab 400 is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
DrivingDriving
UNSAFE
Bevacimab 400 may cause side effects which could affect your ability to drive. Sleepiness and fainting have been reported with Bevacimab 400 and this ma... View More
KidneyKidney
SAFE IF PRESCRIBED
Bevacimab 400 is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Bevacimab 400 may not be ... View More
LiverLiver
SAFE IF PRESCRIBED
Bevacimab 400 is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Bevacimab 400 may not be n... View More
descriptionMedical Overview

Introduction

Bevacimab 400 is an anticancer medication. It is used in the treatment of cancer of colon and rectum, non-small cell lung cancer, kidney cancer, brain t... View More

Uses of Bevacimab 400

  • Cancer of colon and rectum
  • Non-small cell lung cancer
  • Kidney cancer
  • Brain tumor
  • Ovarian cancer
  • Cervical cancer

Side effects of Bevacimab 400

Common
  • Rectal bleeding
  • Taste change
  • Headache
  • Nosebleeds
  • Back pain
  • Dry skin
  • High blood pressure
  • Protein in urine
  • Inflammation of the nose

How to use Bevacimab 400

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Bevacimab 400 works

Bevacimab 400 is a anti-angiogenic medication. It works by blocking a protein called vascular endothelial growth factor (VEGF). This stops the formation... View More

What if you forget to take Bevacimab 400?

If you miss a dose of Bevacimab 400, please consult your doctor.

quick tipsQuick Tips
  • Bevacimab 400 is an effective, first-line option when used together with other medicines for certain types of cancers such as colorectal, lung, cervical... View More
  • Bevacimab 400 is given as an infusion. Your doctor or nurse will monitor you for signs of an infusion reaction such as high blood pressure and trouble b... View More
  • It can lower your wound healing ability. Inform your doctor that you are taking this medication before undergoing any surgical procedure.
  • It can increase the risk of bleeding. Inform your doctor if you notice any unusual bleeding or bleeding that doesn't stop easily.
  • Your doctor may regularly check your blood pressure and levels of protein in your urine while you are on Bevacimab 400.
descriptionBrief Description

Indication

Colo-rectal cancer, Lung cancers, Renal cancers, Ovarian cancers, Breast cancers, glioblastoma multiforme of the brain, Exudative ARMD

Administration

IV Preparation Aseptically withdraw necessary amount & dilute in a total volume of 100 mL NS Diluted solutions for infusion may be stored at 2-8°C f... View More

Adult Dose

General: Bevacizumab should be prepared by a healthcare professional using aseptic technique. The initial Bevacizumab dose should be delivered over 90 m... View More

Contraindication

Hypersensitivity to any component Recent hemoptysis

Mode of Action

Bevacizumab binds to VEGF, the key driver of vasculogenesis and angiogenesis, and thereby inhibits the binding of VEGF to its receptors, Flt-1 (VEGFR-1)... View More

Precaution

Gastrointestinal perforations Gastrointestinal (GI) perforation, fistula formation, and/or intra-abdominal abscess unrelated to therapy duration ... View More

Side Effect

>10% Weakness (73-74%),Hypertension (23-67%; grades 3/4: 8-18%),Pain (61-62%),Abdominal pain (50-61%; grades 3/4: 8%),Vomiting (47-52%, grades 3/4:6-11... View More

Pregnancy Category Note

Pregnancy Based on findings from animal studies and its mechanism of action, drug may cause fetal harm in pregnant women Limited postmarketing rep... View More

Interaction

Irinotecan/5–fluorouracil/leucovorin The incidence of epistaxis and grade 1 or 2 hemorrhage (including GI hemorrhage, minor gum bleeding, vaginal hemor... View More

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descriptionDisclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More