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Sitalia M 500 XR500mg+50mg

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Delta Pharma Limited
Generic: Metformin Hydrochloride + Sitagliptin
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descriptionSafety Advices
It is unsafe to consume alcohol with Sitalia M 500 XR.
Sitalia M 500 XR is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; howev... View More
Sitalia M 500 XR is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the ... View More
Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.
Sitalia M 500 XR should be used with caution in patients with kidney disease. Dose adjustment of Sitalia M 500 XR may be needed. Please consult your doc... View More
Sitalia M 500 XR is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Sitalia M 500 XR may no... View More
descriptionMedical Overview


Sitalia M 500 XR is a combination of two medicines that control high blood sugar levels in people with type 2 diabetes mellitus. This helps prevent seri... View More

Uses of Sitalia M 500 XR

  • Type 2 diabetes mellitus

Side effects of Sitalia M 500 XR

  • Diarrhea
  • Nausea
  • Vomiting
  • Upset stomach
  • Headache
  • Nasal congestion (stuffy nose)
  • Sore throat
  • Respiratory tract infection
  • Hypoglycaemia (low blood sugar level) in combination with insulin or sulphonylurea

How to use Sitalia M 500 XR

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Sitalia M 500 XR is to be ... View More

How Sitalia M 500 XR works

Sitalia M 500 XR is a combination of two antidiabetic medicines: Sitagliptin and Metformin. They help your pancreas produce more insulin, facilitate eff... View More

quick tipsQuick Tips
  • Take it with food to lower your chance of having an upset stomach.
  • Chances of weight gain and low blood sugar are lesser as compared to other diabetes medicines.
  • Inform your doctor about your diabetes treatment if you are due to have surgery under a general anaesthetic.
  • Tell your doctor immediately if you experience any deep or rapid breathing, persistent nausea, vomiting, and stomach pain as Janumet XR CP Tablet may ca... View More
descriptionBrief Description


Type 2 DM


Should be taken with food.

Adult Dose

Oral Type 2 DM The recommended starting dose in patients not currently treated with Metformin Initially 50 mg/500 mg bd. The starting dose in pat... View More

Child Dose

<18 years: Safety and efficacy not established

Renal Dose

Renal impairment Obtain eGFR before starting metformin eGFR <30 mL/min/1.73 m²: Contraindicated eGFR 30-45 mL/min/1.73 m²: Not recommended to initiat... View More


Renal dysfunction, e.g., serum creatinine >1.5 mg/dL [males], >1.4 mg/dL [females] or abnormal creatinine clearance. Metabolic acidosis, including dia... View More

Mode of Action

Sitagliptin: Dipeptidyl peptidase 4 (DPP-4) inhibitor, thereby increasing and prolonging incretin hormone activity which are inactivated by DPP-4 enzyme... View More


Not for use in type 1 DM or treatment of ketoacidosis. Discontinue use if pancreatitis is suspected. Renal & hepatic impairment. Sulfonylurea- or insuli... View More

Side Effect

1-10% Abdominal pain (2.2%),Diarrhea (2.4%),Hypoglycemia (2.1%),Nausea (1.3%),Vomiting (1.1%) Frequency Not Defined Exfoliative disorder of skin of... View More


Additive effect w/ sulfonylureas. Thiazide diuretics, corticosteroids, phenothiazines, OC, sympathomimetics, niacin, Ca channel blockers and isoniazid m... View More

Alternative brand for Sitalia M 500 XR
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The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More

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