Manisol 20% IV20%
Infusion
Orion Pharma Ltd.
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| Alcohol | CONSULT YOUR DOCTOR It is not known whether it is safe to consume alcohol with Manisol 20% IV. Please consult your doctor. |
| Pregnancy | CONSULT YOUR DOCTOR Manisol 20% IV may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the dev... View More |
| Breastfeeding | SAFE IF PRESCRIBED Manisol 20% IV is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the ba... View More |
| Driving | SAFE Manisol 20% IV does not usually affect your ability to drive. |
| Kidney | SAFE IF PRESCRIBED Manisol 20% IV is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Manisol 20% IV may not b... View More |
| Liver | CONSULT YOUR DOCTOR There is limited information available on the use of Manisol 20% IV in patients with liver disease. Please consult your doctor. |
Introduction
Manisol 20% IV is a medicine used in the treatment of acute renal (kidney) failure, cerebral edema (accumulation of excessive fluid in the brain) and to... View More
Uses of Manisol 20% IV
- Acute renal failure
- Cerebral edema (accumulation of excessive fluid in the brain)
- Glaucoma
Side effects of Manisol 20% IV
- Nausea
- Vomiting
- Headache
- Dehydration
How to use Manisol 20% IV
Your doctor or nurse will give you this medicine. Kindly do not self-administer.
How Manisol 20% IV works
Manisol 20% IV is an inert substance with high osmotic pressure. It draws water into the kidney, which in turn increases the amount of urine production.... View More
What if you forget to take Manisol 20% IV?
If you miss a dose of Manisol 20% IV, please consult your doctor.
- It is given as an injection into the veins by a doctor or healthcare professional.
- Your doctor may get regular blood tests done to monitor sodium and potassium level, kidney function, and lung function while you are taking this medicin... View More
- Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
Indication
Chronic bronchitis, Cerebral oedema, Oliguric phase of renal failure, Raised intracranial pressure, Renal function testing, Transurethral prostatic rese... View More
Adult Dose
Intravenous Oliguric phase of renal failure Adult: 50-100 g in a 24-hr period by IV infusion. Adjust rate of administration to maintain a urine flow o... View More
Child Dose
Intravenous Edema 0.25-1 g/kg IV initially; maintenance dose of 0.25-0.5 g/kg IV q4-6hr Anuria/Oliguria Test dose: 0.2 g/kg IV over 3-5 minutes; ... View More
Contraindication
Pulmonary congestion or oedema; intracranial bleeding; CHF; metabolic oedema with abnormal capillary fragility; anuria due to severe renal disease; seve... View More
Mode of Action
Mannitol increases urinary output by inhibiting tubular reabsorption of water and electrolytes. It raises the osmotic pressure of the plasma allowing wa... View More
Precaution
Hypervolaemia; urinary tract obstruction; check for signs of fluid and electrolyte imbalance. Should not be administered with whole blood. Pregnancy, la... View More
Side Effect
Fluid and electrolyte imbalance; acidosis (with high doses). Nausea, vomiting, thirst; headache, dizziness, convulsions, chills, fever; tachycardia, che... View More
Interaction
Increased nephrotoxicity with ciclosporin.
Alternative brand for Manisol 20% IV
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More