Eposin IV100mg/5ml
Injection
Additional Offers
Show allAlcohol | CONSULT YOUR DOCTOR It is not known whether it is safe to consume alcohol with Eposin IV. Please consult your doctor. |
Pregnancy | CONSULT YOUR DOCTOR Eposin IV is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in... View More |
Breastfeeding | UNSAFE Eposin IV is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby. |
Driving | SAFE Eposin IV does not usually affect your ability to drive. |
Kidney | CAUTION Eposin IV should be used with caution in patients with kidney disease. Dose adjustment of Eposin IV may be needed. Please consult your doctor.
Use of Ep... View More |
Liver | CAUTION Eposin IV should be used with caution in patients with liver disease. Dose adjustment of Eposin IV may be needed. Please consult your doctor.
Use of Epo... View More |
Introduction
Eposin IV is used to treat different cancers of lung, and testicles. It is also sometimes used to treat some other kinds of cancer in both men and women... View More
Uses of Eposin IV
- Small cell lung cancer
- Testicular cancer
Side effects of Eposin IV
- Anemia (low number of red blood cells)
- Decreased blood cells (red cells, white cells, and platelets)
- Decreased white blood cell count
- Diarrhea
- Hair loss
- Liver damage
- Low blood platelets
- Nausea
- Rash
- Stomatitis (Inflammation of the mouth)
- Vomiting
How to use Eposin IV
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Eposin IV works
Eposin IV is an anti-cancer medication. It works by suppressing the activity of an enzyme (topoisomerase II) involved in DNA multiplication of the cance... View More
Indication
Lung cancer, Testicular cancer
Adult Dose
Intravenous Testicular Cancer 50-100 mg/m²/day IV on days 1-5, OR 100 mg/m²/day IV on days 1, 3, 5 Repeat q3-4week Small-Cell Lung Cancer 35 mg... View More
Renal Dose
Renal Impairment CrCl >50 mL/min: Dose adjustment not necessary CrCl 15-50 mL/min: 75% of regular dose CrCl < 15 mL/min: Not studied; consider furthe... View More
Contraindication
Hypersensitivity, pregnancy, lactation.
Mode of Action
Etoposide is a derivative of podophyllotoxin that inhibits DNA synthesis resulting in the arrest of the cell cycle. At low doses, it inhibits cells from... View More
Precaution
Skin reactions may occur with accidental exposure; renal or hepatic disease. Periodic CBCs should be done before, during and after therapy. Increased ri... View More
Side Effect
>10% Leukopenia (60-91%),Nausea and Vomiting (30-40%),Thrombocytopenia (28-41%),Alopecia (20-90%),Anorexia (13%),Diarrhea (13%),Leukopenia (60-91%),Ane... View More
Pregnancy Category Note
Pregnancy: Based on animal data and its mechanism of action, etoposide can cause fetal harm when administered to a pregnant woman; etoposide, the active... View More
Interaction
Synergism with other cytotoxic drugs. Caution when admin with drugs that inhibit phosphatase activity. Cyclosporin A may reduce the clearance of etoposi... View More
Alternative brand for Eposin IV
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More