Introduction
Azonam is an antibiotic used to prevent or treat a wide variety of bacterial infections. This may include infections of the urinary tract, blood, brain,... View More
Uses of Azonam
Side effects of Azonam
How to use Azonam
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Azonam works
Azonam is an antibiotic. It kills bacteria by preventing them from forming the bacterial protective covering (cell wall) which is needed for them to sur... View More
Indication
Bone and joint infections, Intra-abdominal infections, Lower respiratory tract infections, Meningitis, Septicaemia, Skin and soft tissue infections, Pel... View More
Administration
Reconstitution: IM: Reconstitute vial w/ at least 3 mL of sterile water for inj, sterile bacteriostatic water for inj, normal saline, or bacteriostati... View More
Adult Dose
Adult: IV/IM Gm-ve infections 1-8 g/day in divided doses depending on severity. Max: 8 g/day. UTI 0.5-1 g 8-12 hrly. IM Cystitis; Gonorrhoea 1 g as ... View More
Child Dose
Child: IV, IM 90–120 mg/kg/day q6–8hr Infants >1 wk: 30 mg/kg every 6 or 8 hr
Renal Dose
Renal impairment CrCl 10-30 mL/min: 1-2 g loading dose, then 50% of usual dosage CrCl <10 mL/min: 1-2 g loading dose, then 25% of usual dosage
Contraindication
Hypersensitivity to aztreonam.
Mode of Action
Aztreonam inhibits bacterial cell wall synthesis due to its high affinity for penicillin-binding protein 3 (PBP-3) of gm-ve bacteria. It is highly resis... View More
Precaution
History of β-lactam hypersensitivity. Renal and hepatic impairment. Childn. Pregnancy and lactation. Monitoring Parameters Monitor for signs of anaphyla... View More
Side Effect
>10% Injection Pain at injection site (12%; children); (2%; adults) Increase in serum transaminases (4-6%) Neutropenia (3-11%, children); (<1%, adul... View More
Pregnancy Category Note
Pregnancy category: B Lactation: Drug is excreted in milk in low concentrations; use not recommended (American Academy of Pediatrics committee states... View More
Interaction
Concurrent use w/ oral anticoagulants may increase prothrombin time.
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More