Azonam1gm/vial
Injection
Incepta Pharmaceuticals Ltd.
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| Alcohol | SAFE Consuming alcohol with Azonam does not cause any harmful side effects. |
| Pregnancy | SAFE IF PRESCRIBED Azonam is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there ... View More |
| Breastfeeding | SAFE IF PRESCRIBED Azonam is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not har... View More |
| Driving | SAFE Azonam does not usually affect your ability to drive. |
| Kidney | CAUTION Azonam should be used with caution in patients with kidney disease. Dose adjustment of Azonam may be needed. Please consult your doctor.
Regular monitor... View More |
| Liver | SAFE IF PRESCRIBED Azonam is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Azonam may not be needed in these... View More |
Introduction
Azonam is an antibiotic used to prevent or treat a wide variety of bacterial infections. This may include infections of the urinary tract, blood, brain,... View More
Uses of Azonam
- Severe bacterial infections
Side effects of Azonam
- Rash
- Injection site reactions (pain, swelling, redness)
- Vomiting
- Nausea
- Diarrhea
How to use Azonam
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Azonam works
Azonam is an antibiotic. It kills bacteria by preventing them from forming the bacterial protective covering (cell wall) which is needed for them to sur... View More
- You have been prescribed Azonam for the treatment of bacterial infections.
- It is given by an injection or drip into a vein or into a muscle in the buttock or thigh.
- Finish the prescribed course, even if you start to feel better. Stopping it early may make the infection come back and harder to treat.
- Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it doesn't stop or if you find blood in your sto... View More
- Inform your doctor immediately if you develop an itchy rash, swelling of the face, throat or tongue or breathing difficulties while taking this medicine... View More
- Inform your doctor if you are pregnant, planning to conceive or breastfeeding.
Indication
Bone and joint infections, Intra-abdominal infections, Lower respiratory tract infections, Meningitis, Septicaemia, Skin and soft tissue infections, Pel... View More
Administration
Reconstitution: IM: Reconstitute vial w/ at least 3 mL of sterile water for inj, sterile bacteriostatic water for inj, normal saline, or bacteriostati... View More
Adult Dose
Adult: IV/IM Gm-ve infections 1-8 g/day in divided doses depending on severity. Max: 8 g/day. UTI 0.5-1 g 8-12 hrly. IM Cystitis; Gonorrhoea 1 g as ... View More
Child Dose
Child: IV, IM 90–120 mg/kg/day q6–8hr Infants >1 wk: 30 mg/kg every 6 or 8 hr
Renal Dose
Renal impairment CrCl 10-30 mL/min: 1-2 g loading dose, then 50% of usual dosage CrCl <10 mL/min: 1-2 g loading dose, then 25% of usual dosage
Contraindication
Hypersensitivity to aztreonam.
Mode of Action
Aztreonam inhibits bacterial cell wall synthesis due to its high affinity for penicillin-binding protein 3 (PBP-3) of gm-ve bacteria. It is highly resis... View More
Precaution
History of β-lactam hypersensitivity. Renal and hepatic impairment. Childn. Pregnancy and lactation. Monitoring Parameters Monitor for signs of anaphyla... View More
Side Effect
>10% Injection Pain at injection site (12%; children); (2%; adults) Increase in serum transaminases (4-6%) Neutropenia (3-11%, children); (<1%, adul... View More
Pregnancy Category Note
Pregnancy category: B Lactation: Drug is excreted in milk in low concentrations; use not recommended (American Academy of Pediatrics committee states... View More
Interaction
Concurrent use w/ oral anticoagulants may increase prothrombin time.
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More