Mabic-2020mg
Tablet
Genvio Pharma Ltd.
Additional Offers
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| Alcohol | CONSULT YOUR DOCTOR It is not known whether it is safe to consume alcohol with Mabic-20. Please consult your doctor. |
| Pregnancy | CONSULT YOUR DOCTOR Mabic-20 is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in ... View More |
| Breastfeeding | UNSAFE Mabic-20 is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby. |
| Driving | UNSAFE Mabic-20 may cause side effects which could affect your ability to drive.
Take special care when driving in case you experience side effects such as diz... View More |
| Kidney | SAFE IF PRESCRIBED Mabic-20 is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Mabic-20 may not be needed in ... View More |
| Liver | SAFE IF PRESCRIBED Mabic-20 is safe to use in patients with liver disease. No dose adjustment of Mabic-20 is recommended. |
Introduction
Mabic-20 is used in the treatment of blood cancer (chronic myeloid leukaemia). It is used in patients whose disease could not be treated with other medi... View More
Uses of Mabic-20
- Blood cancer (Chronic myeloid leukaemia)
Side effects of Mabic-20
- Abdominal pain
- Anemia (low number of red blood cells)
- Breathing problems
- Fatigue
- Fever
- Headache
- Infection
- Low blood platelets
- Musculoskeletal (bone, muscle or joint) pain
- Nausea
- Rash
- Vomiting
How to use Mabic-20
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Mabic-20 may be taken with... View More
How Mabic-20 works
Mabic-20 is an anti-cancer medication. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps to stop... View More
What if you forget to take Mabic-20?
If you miss a dose of Mabic-20, skip it and continue with your normal schedule. Do not double the dose.
- Take it with or without food, preferably at the same time each day.
- Diarrhea may occur as a side effect. Drink plenty of fluids and inform your doctor if it doesn't stop or if you find blood in your stools.
- Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine and for a month after you stop taking it.
- Monitor your blood pressure regularly while taking this medication. Inform your doctor if you notice symptoms of very high blood pressure such as severe... View More
- It may cause serious bleeding problem. Inform your doctor if you get headaches, stomach pain or if you notice blood in your urine or stools.
- Do not take this medicine if you are pregnant, planning to conceive or breastfeeding.
Indication
Chronic myeloid leukaemia
Administration
May be taken with or without food. Swallow whole, do not break/crush/cut.
Adult Dose
Oral Chronic myeloid leukaemia Adult: Chronic phase CML: Initially, 100 mg once daily, may increase up to 140 mg once daily. Accelerated, myeloid or l... View More
Contraindication
Concomitant use w/ CYP3A4 inhibitors (e.g. atazanavir, clarithromycin, erythromycin, indinavir, itraconazole, ketoconazole, nefazodone, nelfinavir, rito... View More
Mode of Action
Dasatinib is an inhibitor of multiple tyrosine kinases. It is used for the treatment of all phases of chronic myeloid leukaemia (CML) and Philadelphia c... View More
Precaution
Patients w/ predisposing factors for QT prolongation (e.g. congenital long QT syndrome, hypokalaemia, hypomagnesaemia, on antiarrhythmic therapy, or rec... View More
Side Effect
>10% Fluid retention, incl CHF, pulm edema, pleural effusion (50%),Diarrhea (49%),Headache (40%),Hemorrhage (40%),Fatigue (39%),Pyrexia (39%),Skin rash... View More
Pregnancy Category Note
Pregnancy Based on limited human data, dasatinib can cause fetal harm when administered to a pregnant woman; adverse pharmacologic effects (eg, hydrops... View More
Interaction
Concomitant use w/ drugs that have narrow therapeutic index (e.g. alfentanil, cisapride, ciclosporin, fentanyl, pimozide, quinidine, simvastatin, siroli... View More
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More