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Mabic-2020mg

Tablet
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Genvio Pharma Ltd.
Generic: Dasatinib
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72.00
MRP
80.00
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descriptionSafety Advices
AlcoholAlcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Mabic-20. Please consult your doctor.
PregnancyPregnancy
CONSULT YOUR DOCTOR
Mabic-20 is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in ... View More
BreastfeedingBreastfeeding
UNSAFE
Mabic-20 is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
DrivingDriving
UNSAFE
Mabic-20 may cause side effects which could affect your ability to drive. Take special care when driving in case you experience side effects such as diz... View More
KidneyKidney
SAFE IF PRESCRIBED
Mabic-20 is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Mabic-20 may not be needed in ... View More
LiverLiver
SAFE IF PRESCRIBED
Mabic-20 is safe to use in patients with liver disease. No dose adjustment of Mabic-20 is recommended.
descriptionMedical Overview

Introduction

Mabic-20 is used in the treatment of blood cancer (chronic myeloid leukaemia). It is used in patients whose disease could not be treated with other medi... View More

Uses of Mabic-20

  • Blood cancer (Chronic myeloid leukaemia)

Side effects of Mabic-20

Common
  • Abdominal pain
  • Anemia (low number of red blood cells)
  • Breathing problems
  • Fatigue
  • Fever
  • Headache
  • Infection
  • Low blood platelets
  • Musculoskeletal (bone, muscle or joint) pain
  • Nausea
  • Rash
  • Vomiting

How to use Mabic-20

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Mabic-20 may be taken with... View More

How Mabic-20 works

Mabic-20 is an anti-cancer medication. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps to stop... View More

What if you forget to take Mabic-20?

If you miss a dose of Mabic-20, skip it and continue with your normal schedule. Do not double the dose.

quick tipsQuick Tips
  • Take it with or without food, preferably at the same time each day.
  • Diarrhea may occur as a side effect. Drink plenty of fluids and inform your doctor if it doesn't stop or if you find blood in your stools.
  • Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine and for a month after you stop taking it.
  • Monitor your blood pressure regularly while taking this medication. Inform your doctor if you notice symptoms of very high blood pressure such as severe... View More
  • It may cause serious bleeding problem. Inform your doctor if you get headaches, stomach pain or if you notice blood in your urine or stools.
  • Do not take this medicine if you are pregnant, planning to conceive or breastfeeding.
descriptionBrief Description

Indication

Chronic myeloid leukaemia

Administration

May be taken with or without food. Swallow whole, do not break/crush/cut.

Adult Dose

Oral Chronic myeloid leukaemia Adult: Chronic phase CML: Initially, 100 mg once daily, may increase up to 140 mg once daily. Accelerated, myeloid or l... View More

Contraindication

Concomitant use w/ CYP3A4 inhibitors (e.g. atazanavir, clarithromycin, erythromycin, indinavir, itraconazole, ketoconazole, nefazodone, nelfinavir, rito... View More

Mode of Action

Dasatinib is an inhibitor of multiple tyrosine kinases. It is used for the treatment of all phases of chronic myeloid leukaemia (CML) and Philadelphia c... View More

Precaution

Patients w/ predisposing factors for QT prolongation (e.g. congenital long QT syndrome, hypokalaemia, hypomagnesaemia, on antiarrhythmic therapy, or rec... View More

Side Effect

>10% Fluid retention, incl CHF, pulm edema, pleural effusion (50%),Diarrhea (49%),Headache (40%),Hemorrhage (40%),Fatigue (39%),Pyrexia (39%),Skin rash... View More

Pregnancy Category Note

Pregnancy Based on limited human data, dasatinib can cause fetal harm when administered to a pregnant woman; adverse pharmacologic effects (eg, hydrops... View More

Interaction

Concomitant use w/ drugs that have narrow therapeutic index (e.g. alfentanil, cisapride, ciclosporin, fentanyl, pimozide, quinidine, simvastatin, siroli... View More

descriptionDisclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More