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Renata Limited
Generic: Drospirenone + Estradiol
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descriptionSafety Advices
Caution is advised when consuming alcohol with Angela. Please consult your doctor.
Angela is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effec... View More
Angela is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. Nonhorm... View More
Angela does not usually affect your ability to drive.
Angela is probably unsafe to use in patients with kidney disease and should be avoided. Please consult your doctor.
Angela is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.
descriptionMedical Overview


Angela is a combination of two medicines used for contraception (to prevent pregnancy) and in the treatment of irregular periods. It helps to prevent re... View More

Uses of Angela

  • Contraception

Side effects of Angela

  • Nausea
  • Stomach pain
  • Headache
  • Weight gain
  • Breast pain
  • Irregular uterine bleeding

How to use Angela

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Angela may be taken with o... View More

How Angela works

Angela is a combined oral contraceptive pill. It works by preventing the release of egg (ovulation) and affecting sperm movement in the womb to prevent ... View More

quick tipsQuick Tips
  • Your doctor has prescribed Angela to help you prevent pregnancy.
  • It also results in lighter, less painful and more regular menstrual bleeding.
  • It may help reduce the risk of ovarian cancer.
  • Take your pill at the same time every day to help you remember to take it.
  • You may experience menstrual irregularities such as spotting or bleeding between menstrual periods or missed periods. Consult your doctor if this persis... View More
  • Do not use Angela if you are obese, over 35, smoke, on prolonged bed rest, or have a history of blood clots.
  • Stop taking this medicine and inform your doctor immediately if you notice unexplained swelling and pain in your limbs, shortness of breath, chest pain,... View More
  • Stop taking Angela and inform your doctor immediately if you notice your skin and whites of the eye turning yellow (jaundice), severe stomach pain, seve... View More
descriptionBrief Description


Hormone replacement therapy (HRT), Climacteric syndrome in postmenopausal women including vasomotor symptoms (such as hot flushes and sweating attacks)... View More


Each pack covers 28 days of treatment. Treatment is continuous, which means that the next pack follows immediately without a break. The tablets are to b... View More

Adult Dose

Hormone Replacement Therapy Oral Tablet 1 tablet PO daily Hepatic impairment In women with mild or moderate hepatic impairment, DRSP is well tole... View More

Renal Dose

Renal Impairment In women with mild or moderate renal impairment, a slight increase of Drug Resistant Streptococcus Pneumoniae exposure was observed bu... View More


Hormone replacement therapy (HRT) should not be started in the presence of any of the conditions listed below. The product should be stopped immediately... View More

Mode of Action

Estradiol: Endogenous estrogen; reduces the release of gonadotropin-releasing hormone from hypothalamus, reduces release of luteinizing hormone (LH) and... View More


Before initiating therapy, all conditions/risk factors mentioned below should be considered when determining the individual benefit/risk of treatment fo... View More

Side Effect

>10% Breast pain (19%) Upper respiratory infection (19%) Abdominal pain (11%) 1-10% Edema Peripheral edema Headache Accidental injury, back pa... View More

Pregnancy Category Note

Pregnancy Category: contraindicated in pregnancy Lactation: enters breast milk/not recommended


Pharmacodynamic interaction with antihypertensive medications and non-steroidal anti-inflammatory drugs (NSAID) Hypertensive women treated with this ... View More


The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More