Introduction
Human Albumin 20% 100 ml is used to treat blood volume loss. It works by replacing the body fluids lost due to excessive trauma, bleeding, surgery, or kidney dialysis. Thus, it is helpful in treating low blood albumin levels.
Human Albumin 20% 100 ml must be administered under the supervision of a healthcare professional. You should not take it if you have any known allergy from this injection. Before taking it, inform the doctor you are suffering from any severe heart disease.
Your doctor may check your blood pressure and ask you to get regular blood tests done while you are using this injection. The most common side effects include flushing (sense of warmth in the face, ears, neck, and trunk), nausea and fever.
Inform your doctor if you are pregnant or breastfeeding or suffering from kidney diseases as a dose adjustment may be required. This injection is safe to use in patients suffering from liver diseases.
Uses of Human Albumin 20% 100 ml
Side effects of Human Albumin 20% 100 ml
Common
- Vomiting
- Flushing (sense of warmth in the face, ears, neck and trunk)
- Fever
- Nausea
- Chills
- Hives
- Slow heart rate
How to use Human Albumin 20% 100 ml
Your doctor or nurse will give you this medicine. Kindly do not self-administer.
How Human Albumin 20% 100 ml works
Human Albumin 20% 100 ml contains human albumin, a natural protein in blood. It works by replacing the blood or body fluids lost due to excessive bleeding, surgery, or kidney dialysis.
What if you forget to take Human Albumin 20% 100 ml?
If you miss a dose of Human Albumin 20% 100 ml, please consult your doctor.
Indication
Burns, Hypovolemia, Hypoalbuminemia, Hypoproteinaemia, Adult Respiratory Distress Syndrome, Nephrosis, Cardiopulmonary Bypass Surgery, Hemolytic Disease of the Newborn, Ovarian Hyperstimulation Syndrome, Acute hypovolaemic shock, Neonatal hyperbilirubinaemia
Adult Dose
Adult: Initially, 25 g of albumin, adjusted according to patient's response. Usual rates of infusion: Up to 1-2 ml/minute (20% solution).
Intravenous Hypoproteinaemia Adult: Up to 2 g/kg daily. Usual rates of infusion: Up to 1-2 ml/minute (20% solution).
Special Populations: Volume admin and rate of infusion must always be individualised according to situation and response. Usual rates of infusion are up to 1-2 ml/min (20% soln).
Child Dose
Child: Up to 1 g/kg, adjusted according to patient's response. Usual rates of infusion: Up to 1-2 ml/minute (20% solution).
Intravenous Neonatal hyperbilirubinaemia Child: 1 g/kg of albumin before exchange transfusion. Usual rates of infusion: Up to 1-2 ml/minute (20% solution).
Special Populations: Volume admin and rate of infusion must always be individualised according to situation and response. Usual rates of infusion are up to 1-2 ml/min (20% soln).
Contraindication
Cardiac failure, severe anaemia, history of hypersensitivity, parenteral nutrition.
Mode of Action
Human albumin increases intravascular oncotic pressure and causes movement of fluids from interstitial into intravascular space. Human albumin solutions are available in various concentrations. Solutions containing 5% human albumin are usually used in hypovolemic patients, whereas more concentrated 25% solutions are recommended in patients in whom fluid and sodium intake must be minimised e.g. patients with hypoproteinaemia or cerebral oedema or in paediatric patients.
Precaution
Hypertension or low cardiac reserve; additional fluids for dehydrated patients. Monitor for signs of cardiac overload in injured or postoperative patients. May carry risk of viral transmission. Volume admin and rate of infusion must always be individualised according to situation and response. Pregnancy, lactation.
Side Effect
Allergic reactions, nausea, vomiting, increased salivation, fever and chills; vascular overload, haemodilution and pulmonary oedema.
Potentially Fatal: Anaphylactic shock.
Pregnancy Category Note
Pregnancy category: C
Lactation: Endogenous albumin found in breast milk; compatible
Interaction
Albumin solution should not be mixed by protein hydrolysates or alcoholic solutions. Risk of atypical reactions to ACE inhibitors in patients undergoing therapeutic plasma exchange with albumin human replacement.