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Xanuric 8080mg

Tablet
rx_reqRequire Prescription
Unimed Unihealth Pharmaceuticals Ltd.
Generic: Febuxostat
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descriptionSafety Advices
AlcoholAlcohol
CAUTION
Caution is advised when consuming alcohol with Xanuric 80. Please consult your doctor.
PregnancyPregnancy
CONSULT YOUR DOCTOR
Xanuric 80 may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the develop... View More
BreastfeedingBreastfeeding
CONSULT YOUR DOCTOR
Xanuric 80 is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
DrivingDriving
UNSAFE
Xanuric 80 may cause side effects which could affect your ability to drive. Xanuric 80 may cause dizziness, sleepiness, blurred vision, numbness or ting... View More
KidneyKidney
CAUTION
Xanuric 80 should be used with caution in patients with severe kidney disease. Dose adjustment of Xanuric 80 may be needed. Please consult your doctor. ... View More
LiverLiver
CAUTION
Xanuric 80 should be used with caution in patients with severe liver disease. Dose adjustment of Xanuric 80 may be needed. Please consult your doctor. L... View More
descriptionMedical Overview

Introduction

Xanuric 80 is a medicine used to treat and prevent gout. Gout happens when there is too much uric acid in your body and it forms into crystals which can... View More

Uses of Xanuric 80

  • Gout

Side effects of Xanuric 80

Common
  • Diarrhea
  • Headache
  • Increased liver enzymes
  • Nausea
  • Skin rash
  • Gout flares

How to use Xanuric 80

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Xanuric 80 may be taken wi... View More

How Xanuric 80 works

Xanuric 80 is a xanthine oxidase inhibitor. It works by decreasing blood uric acid, which is the chemical that causes gout.

What if you forget to take Xanuric 80?

If you miss a dose of Xanuric 80, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to you... View More

quick tipsQuick Tips
  • Your doctor has prescribed Xanuric 80 to reduce episodes of gout attack.
  • Take it at the same time every day, with or without food.
  • Take plenty of fluids (2-3 litres) daily while on Xanuric 80.
  • When you first start taking this medicine, you might have more gout attacks. Do not stop Xanuric 80 on having an acute attack of gout as that could make... View More
  • Do not consume alcohol while taking this medicine as it may cause your gout to flare up.
  • Stop taking this medicine and inform your doctor straight away if you have symptoms like rash, itchiness, difficulties in breathing, fever or swelling o... View More
descriptionBrief Description

Indication

Gout, Hyperuricemia

Administration

May be taken with or without food. May be taken w/o regard to antacid use.

Adult Dose

Chronic Gout 40 mg/day PO initially; maintenance: 40-80 mg/day; increased if serum uric acid is >6 mg/mL after 2 weeks Hepatic impairment Mild to m... View More

Child Dose

Safety and efficacy not established

Renal Dose

Renal impairment Mild to moderate (CrCl 30-89 mL/min): Dosage adjustment not necessary Severe (CrCl <30 mL/min): Data not available; use with caution

Contraindication

Patients being treated with azathioprine, mercaptopurine, or theophylline.

Mode of Action

Febuxostat selectively inhibits xanthine oxidase, the enzyme that catalyses the conversion of hypoxanthine to xanthine to uric acid, thereby decreasing ... View More

Precaution

Cardiovascular death Patients with established cardiovascular (CV) disease treated with febuxostat had a higher rate of CV death compared with those tr... View More

Side Effect

>1% Arthralgia,Elevated liver function test (LFT) results,Liver function abnormalities,Nausea,Rash

Pregnancy Category Note

Pregnancy Limited available data in pregnant women are insufficient to inform a drug associated risk of adverse developmental outcomes Animal data ... View More

Interaction

May increase plasma conc of mercaptopurine, azathioprine. Alteration of metabolism of xanthine oxidase substrate drugs (eg theophylline).

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descriptionDisclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More