Herceptin 440440mg/20ml
Injection
Roche Bangladesh Pharmaceutical
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| Alcohol | UNSAFE Herceptin 440 may cause excessive drowsiness with alcohol. |
| Pregnancy | CONSULT YOUR DOCTOR Herceptin 440 is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe i... View More |
| Breastfeeding | CONSULT YOUR DOCTOR Herceptin 440 is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. |
| Driving | CONSULT YOUR DOCTOR It is not known whether Herceptin 440 alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate a... View More |
| Kidney | SAFE IF PRESCRIBED Herceptin 440 is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Herceptin 440 may not be ... View More |
| Liver | CONSULT YOUR DOCTOR There is limited information available on the use of Herceptin 440 in patients with liver disease. Please consult your doctor. |
Introduction
Herceptin 440 is used in the treatment of breast and stomach cancer. It works by killing the cancer cells by inhibiting HER2 (human epidermal growth fac... View More
Uses of Herceptin 440
- Breast cancer
- Stomach cancer
Side effects of Herceptin 440
- Anemia (low number of red blood cells)
- Chills
- Common cold
- Cough
- Decreased blood cells (red cells, white cells, and platelets)
- Diarrhea
- Fatigue
- Fever
- Headache
- Heart failure
- Infection
- Insomnia (difficulty in sleeping)
- Mucosal inflammation
- Nausea
- Rash
- Stomatitis (Inflammation of the mouth)
- Taste change
- Upper respiratory tract infection
- Weight loss
How to use Herceptin 440
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Herceptin 440 works
Herceptin 440 is a recombinant IgG1 monoclonal antibody. It works against the HER2 (human epidermal growth factor receptor protein) receptors which are ... View More
What if you forget to take Herceptin 440?
If you miss a dose of Herceptin 440, please consult your doctor.
- It is given as an injection into your vein or under the skin, usually over 1 hour.
- Use effective contraception method to prevent pregnancy while taking this medicine and for 7 months after you stop the treatment.
- Your doctor will monitor your heart regularly while taking this medicine. Inform your doctor if you notice symptoms such as breathlessness, cough, shive... View More
- Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
Indication
Breast cancer, Gastric cancer
Administration
IV Administration Not for IV push or bolus administration Administer initial IV infusion over 90 min Subsequent weekly IV infusions may be administer... View More
Adult Dose
Intravenous Breast Cancer Adjuvant treatment Indicated for adjuvant treatment of HER-2 overexpressing breast cancer Administer during and following ... View More
Child Dose
Safety and efficacy not established
Contraindication
Lactation (start only 6 mth after last dose of drug). Do not admin by rapid IV or bolus inj.
Mode of Action
Trastuzumab, a monoclonal antibody, has action directed against a cell surface protein produced by human epidermal growth factor receptor 2 (HER2). It i... View More
Precaution
Patient w/ pre-existing CV and pulmonary disease; extensive pulmonary tumour involvement. Pregnancy and lactation. Monitoring Parameters Monitor cardiac... View More
Side Effect
>10% Pain (47%),Asthenia (42%),Fever (36%),Nausea (33%),Chills (32%),Cough (26%),Headache (26%),Diarrhea (25%),Vomiting (23%),Abdominal pain (22%),Back... View More
Interaction
Increased risk of severe cardiotoxicity with anthracyclines. Increased risk of leukopenia and anaemia in combination chemotherapy (e.g. paclitaxel). Pac... View More
Alternative brand for Herceptin 440
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More