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Pentothal Sodium

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Unimed Unihealth Pharmaceuticals Ltd.
Generic: Thiopental Sodium
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descriptionSafety Advices
It is unsafe to consume alcohol with Pentothal Sodium.
Pentothal Sodium may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the d... View More
Pentothal Sodium is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and ... View More
Pentothal Sodium may cause side effects which could affect your ability to drive.
Pentothal Sodium should be used with caution in patients with kidney disease. Dose adjustment of Pentothal Sodium may be needed. Please consult your doc... View More
Pentothal Sodium should be used with caution in patients with liver disease. Dose adjustment of Pentothal Sodium may be needed. Please consult your doct... View More
descriptionMedical Overview


Pentothal Sodium is a prescription medicine used for producing general anesthesia. It is also used as truth serum because it alters certain functions in... View More

Uses of Pentothal Sodium

  • Anesthesia

Side effects of Pentothal Sodium

  • Injection site reactions (pain, swelling, redness)
  • Drowsiness
  • Skin rash
  • Nausea
  • Vomiting
  • Diarrhea
  • Vertigo

How to use Pentothal Sodium

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Pentothal Sodium works

Pentothal Sodium is a general anaesthetic. It works by causing reversible loss of consciousness to allow surgery without pain and distress.

quick tipsQuick Tips
  • Pentothal Sodium is used to facilitate surgery without pain and distress.
  • It is given as an injection into veins under the supervision of a doctor.
  • It can cause severe drowsiness lasting for several hours. Do not drive or do anything that requires alertness for at least 24 hours.
  • Inform your doctor if you have liver disease, thyroid disorder, severe heart disease, severe low blood pressure or a severe breathing disorder.
  • Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
descriptionBrief Description


Status epilepticus, Induction of anesthesia, Reduction of raised intracranial pressure

Adult Dose

Intravenous Induction of anaesthesia Adult: 100-150 mg of a 2.5 or 5% solution injected over 10-15 sec repeated every 30-60 sec according to response ... View More

Child Dose

Intravenous Induction of anaesthesia Child: 2-7 mg/kg over 10-15 seconds; repeated after 1 minute if needed.. Status epilepticus Child: 5 mg/kg b... View More

Renal Dose

Renal impairment: Dose reduction may be needed.


Thiopental Sodium for Injection is contraindicated in patients with severe respiratory embarrassment, hypersensitivity to barbiturates, status asthmatic... View More

Mode of Action

Thiopental sodium, a short-acting barbiturate anaesthetic, is a CNS depressant inducing hypnosis and anaesthesia but not analgesia. It has also been use... View More


Hypovolaemia; history of severe asthma, severe cardiac disease, severe anaemia, hyperkalaemia, toxaemia, myasthenia gravis, myxoedema; severe renal or h... View More

Side Effect

Coughing, hiccupping, sneezing, muscle twitching, laryngospasm, bronchospasm. IV: tissue necrosis (if extravasation occurs). Intra-arterial: Severe arte... View More


Possible increase in difficulty in producing anaesthesia in patients taking alcohol or CNS depressants. Additive action with other CNS depressants inclu... View More


The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More