Introduction
Delentin is an anti-helminitic medication. It is used in the treatment of worm infections. It works by killing the worms that cause infection. The killed worms are then passed in the stool.
Delentin should be used in the dose and duration as advised by your doctor. It should be taken with food, preferably at a fixed time. Avoid skipping any doses and finish the full course of treatment even if you feel better. Do not take a double dose to make up for a missed dose. Simply take the next dose as planned.
Some people may experience headache, dizziness, nausea, hair loss and vomiting, as the side effects of this medicine. Please consult your doctor if these side effects persist for a longer duration. You may be monitored with blood tests and liver function tests throughout your treatment.
Side effects of Delentin
Common
- Headache
- Dizziness
- Nausea
- Hair loss
- Vomiting
- Abnormal liver function tests
- Fever
- Abdominal pain
- Vertigo
How to use Delentin
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Delentin may be taken with or without food, but it is better to take it at a fixed time.
How Delentin works
Delentin is an antihelmintic medication. It works by binding to the muscle and nerve cells of worms, causing their paralysis. The worms are unable to move and are cleared naturally in stool.
Indication
Enterobiasis, Ascariasis, Worm infections, Trichinosis
Administration
May be taken with or without food.
Adult Dose
Oral
Single or mixed infections due to susceptible worms
Adult: 10 mg/kg as a single dose.
Ascariasis
Adult: 5 mg/kg as a single dose. Max: 1 g/dose.
For mass treatment programmes: 2.5 mg/kg as a single dose given 3-4 times a yr.
Necatoriasis
Adult: 10 mg/kg daily for 3-4 days or 20 mg/kg daily for 2 days.
Enterobiasis
Adult: 10 mg/kg repeated once after 2-4 wk. Max dose: 1 g/dose.
Trichinosis
Adult: 10 mg/kg daily for 5 days.
Child Dose
<2 years: Safety and efficacy not established
Oral
Single or mixed infections due to susceptible worms
Child: 10 mg/kg as a single dose.
Contraindication
Hypersensitivity
Mode of Action
Pyrantel is effective against roundworms (Ascaris), threadworms (Enterobius), hookworms and Trichostrongylus. Not effective against whipworm. Acts by paralysing the worms which get detached and are excreted by intestinal peristalsis.
Precaution
Liver dysfunction, anaemia or severe malnutrition. Treat members in close contact with the patient.
Side Effect
Anorexia, nausea, vomiting, abdominal cramps, drowsiness, insomnia, diarrhoea, tenesmus, SGOT elevations, headache, dizziness, rash.
Interaction
Potentially Fatal: Mutually antagonistic with piperazine.