Bevastim 400400mg/16ml
Injection
Beacon Pharmaceuticals Ltd.
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| Alcohol | CONSULT YOUR DOCTOR It is not known whether it is safe to consume alcohol with Bevastim 400. Please consult your doctor. |
| Pregnancy | CONSULT YOUR DOCTOR Bevastim 400 may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the devel... View More |
| Breastfeeding | CONSULT YOUR DOCTOR Bevastim 400 is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. |
| Driving | UNSAFE Bevastim 400 may cause side effects which could affect your ability to drive.
Sleepiness and fainting have been reported with Bevastim 400 and this may ... View More |
| Kidney | SAFE IF PRESCRIBED Bevastim 400 is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Bevastim 400 may not be ne... View More |
| Liver | SAFE IF PRESCRIBED Bevastim 400 is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Bevastim 400 may not be nee... View More |
Introduction
Bevastim 400 is an anticancer medication. It is used in the treatment of cancer of colon and rectum, non-small cell lung cancer, kidney cancer, brain tu... View More
Uses of Bevastim 400
- Cancer of colon and rectum
- Non-small cell lung cancer
- Kidney cancer
- Brain tumor
- Ovarian cancer
- Cervical cancer
Side effects of Bevastim 400
- Rectal bleeding
- Taste change
- Headache
- Nosebleeds
- Back pain
- Dry skin
- High blood pressure
- Protein in urine
- Inflammation of the nose
How to use Bevastim 400
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Bevastim 400 works
Bevastim 400 is a anti-angiogenic medication. It works by blocking a protein called vascular endothelial growth factor (VEGF). This stops the formation ... View More
What if you forget to take Bevastim 400?
If you miss a dose of Bevastim 400, please consult your doctor.
- Bevastim 400 is an effective, first-line option when used together with other medicines for certain types of cancers such as colorectal, lung, cervical,... View More
- Bevastim 400 is given as an infusion. Your doctor or nurse will monitor you for signs of an infusion reaction such as high blood pressure and trouble br... View More
- It can lower your wound healing ability. Inform your doctor that you are taking this medication before undergoing any surgical procedure.
- It can increase the risk of bleeding. Inform your doctor if you notice any unusual bleeding or bleeding that doesn't stop easily.
- Your doctor may regularly check your blood pressure and levels of protein in your urine while you are on Bevastim 400.
Indication
Colo-rectal cancer, Lung cancers, Renal cancers, Ovarian cancers, Breast cancers, glioblastoma multiforme of the brain, Exudative ARMD
Administration
IV Preparation Aseptically withdraw necessary amount & dilute in a total volume of 100 mL NS Diluted solutions for infusion may be stored at 2-8°C f... View More
Adult Dose
General: Bevacizumab should be prepared by a healthcare professional using aseptic technique. The initial Bevacizumab dose should be delivered over 90 m... View More
Contraindication
Hypersensitivity to any component Recent hemoptysis
Mode of Action
Bevacizumab binds to VEGF, the key driver of vasculogenesis and angiogenesis, and thereby inhibits the binding of VEGF to its receptors, Flt-1 (VEGFR-1)... View More
Precaution
Gastrointestinal perforations Gastrointestinal (GI) perforation, fistula formation, and/or intra-abdominal abscess unrelated to therapy duration ... View More
Side Effect
>10% Weakness (73-74%),Hypertension (23-67%; grades 3/4: 8-18%),Pain (61-62%),Abdominal pain (50-61%; grades 3/4: 8%),Vomiting (47-52%, grades 3/4:6-11... View More
Pregnancy Category Note
Pregnancy Based on findings from animal studies and its mechanism of action, drug may cause fetal harm in pregnant women Limited postmarketing rep... View More
Interaction
Irinotecan/5–fluorouracil/leucovorin The incidence of epistaxis and grade 1 or 2 hemorrhage (including GI hemorrhage, minor gum bleeding, vaginal hemor... View More
Alternative brand for Bevastim 400
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More