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Barif 8080mg
Tablet
Square Pharmaceuticals Ltd.
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LiverMedical OverviewIntroduction
Barif 80 is a medicine used to treat and prevent gout. Gout happens when there is too much uric acid in your body and it forms into crystals which can a... View More
Uses of Barif 80
- Gout
Side effects of Barif 80
- Diarrhea
- Headache
- Increased liver enzymes
- Nausea
- Skin rash
- Gout flares
How to use Barif 80
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Barif 80 may be taken with... View More
How Barif 80 works
Barif 80 is a xanthine oxidase inhibitor. It works by decreasing blood uric acid, which is the chemical that causes gout.
What if you forget to take Barif 80?
If you miss a dose of Barif 80, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your ... View More
Quick Tips- Your doctor has prescribed Barif 80 to reduce episodes of gout attack.
- Take it at the same time every day, with or without food.
- Take plenty of fluids (2-3 litres) daily while on Barif 80.
- When you first start taking this medicine, you might have more gout attacks. Do not stop Barif 80 on having an acute attack of gout as that could make a... View More
- Do not consume alcohol while taking this medicine as it may cause your gout to flare up.
- Stop taking this medicine and inform your doctor straight away if you have symptoms like rash, itchiness, difficulties in breathing, fever or swelling o... View More
Brief DescriptionIndication
Gout, Hyperuricemia
Administration
May be taken with or without food. May be taken w/o regard to antacid use.
Adult Dose
Chronic Gout 40 mg/day PO initially; maintenance: 40-80 mg/day; increased if serum uric acid is >6 mg/mL after 2 weeks Hepatic impairment Mild to m... View More
Child Dose
Safety and efficacy not established
Renal Dose
Renal impairment Mild to moderate (CrCl 30-89 mL/min): Dosage adjustment not necessary Severe (CrCl <30 mL/min): Data not available; use with caution
Contraindication
Patients being treated with azathioprine, mercaptopurine, or theophylline.
Mode of Action
Febuxostat selectively inhibits xanthine oxidase, the enzyme that catalyses the conversion of hypoxanthine to xanthine to uric acid, thereby decreasing ... View More
Precaution
Cardiovascular death Patients with established cardiovascular (CV) disease treated with febuxostat had a higher rate of CV death compared with those tr... View More
Side Effect
>1% Arthralgia,Elevated liver function test (LFT) results,Liver function abnormalities,Nausea,Rash
Pregnancy Category Note
Pregnancy Limited available data in pregnant women are insufficient to inform a drug associated risk of adverse developmental outcomes Animal data ... View More
Interaction
May increase plasma conc of mercaptopurine, azathioprine. Alteration of metabolism of xanthine oxidase substrate drugs (eg theophylline).
Alternative brand for Barif 80
DisclaimerThe information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More
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