Brexi 11mg
Tablet
Eskayef Pharmaceuticals Ltd.
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Indication
Indicated for schizophrenia, Indicated as adjunctive treatment for major depressive disorder
Administration
May take with or without food
Adult Dose
Schizophrenia Indicated for schizophrenia Recommended starting dose: 1 mg PO qDay on Days 1 through 4 Recommended target dose: 2-4 mg PO qDay; titrat... View More
Renal Dose
Renal impairment Moderate, severe, or ESRD (CrCl <60 mL/min) MDD: Not to exceed 2 mg/day Schizophrenia: Not to exceed 3 mg/day
Contraindication
Hypersensitivity; reactions have included rash, facial swelling, urticaria, and angioedema
Mode of Action
Serotonin-dopamine activity modulator (SDAM) that acts as a partial agonist at 5-HT1A and dopamine D2 receptors at similar potency, and an antagonist at... View More
Precaution
Increased mortality in elderly patients with dementia-related psychosis; in placebo-controlled trials with risperidone, aripiprazole, and olanzapine in ... View More
Side Effect
>10% Akathisia (4-14%) 1-10% Headache (4-9%) Weight increased (3-8%) Nasopharyngitis (1-7%) Extrapyramidal symptoms, excluding akathisia (5-6%) ... View More
Pregnancy Category Note
Pregnancy Adequate and well-controlled studies have not been conducted with brexpiprazole in pregnant women to inform drug-associated risks; however, n... View More
Alternative brand for Brexi 1
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More