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Brexi 0.50.5mg

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Eskayef Pharmaceuticals Ltd.
Generic: Brexpiprazole
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descriptionMedical Overview


Indicated for schizophrenia, Indicated as adjunctive treatment for major depressive disorder


May take with or without food

Adult Dose

Schizophrenia Indicated for schizophrenia Recommended starting dose: 1 mg PO qDay on Days 1 through 4 Recommended target dose: 2-4 mg PO qDay; titrat... View More

Renal Dose

Renal impairment Moderate, severe, or ESRD (CrCl <60 mL/min) MDD: Not to exceed 2 mg/day Schizophrenia: Not to exceed 3 mg/day


Hypersensitivity; reactions have included rash, facial swelling, urticaria, and angioedema

Mode of Action

Serotonin-dopamine activity modulator (SDAM) that acts as a partial agonist at 5-HT1A and dopamine D2 receptors at similar potency, and an antagonist at... View More


Increased mortality in elderly patients with dementia-related psychosis; in placebo-controlled trials with risperidone, aripiprazole, and olanzapine in ... View More

Side Effect

>10% Akathisia (4-14%) 1-10% Headache (4-9%) Weight increased (3-8%) Nasopharyngitis (1-7%) Extrapyramidal symptoms, excluding akathisia (5-6%) ... View More

Pregnancy Category Note

Pregnancy Adequate and well-controlled studies have not been conducted with brexpiprazole in pregnant women to inform drug-associated risks; however, n... View More

Alternative brand for Brexi 0.5
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The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More