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It is unsafe to consume alcohol with Sinergix.
Sinergix may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developin... View More
Sinergix is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby. Co... View More
Sinergix may cause side effects which could affect your ability to drive. Sinergix may cause side effects such as drowsiness and blurred vision. If this... View More
Sinergix should be used with caution in patients with kidney disease. Dose adjustment of Sinergix may be needed. Please consult your doctor.
Sinergix should be used with caution in patients with liver disease. Dose adjustment of Sinergix may be needed. Please consult your doctor.
Sinergix is a pain relieving medicine. It is used in various conditions such as muscle ache, back pain, joint pain, menstrual cramps, and toothache. Si... View More
Uses of Sinergix
- Pain relief
Side effects of Sinergix
- Dryness in mouth
How to use Sinergix
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Sinergix may be taken with... View More
How Sinergix works
Sinergix is a combination of two medicines: Paracetamol/Acetaminophen and Tramadol. Paracetamol/Acetaminophen is an analgesic (pain reliever) which work... View More
- Use only for severe acute pain for not more than 5 days.
- Prolonged use may result in physical and psychological dependence even at recommended dosages.
- It causes sleepiness or drowsiness. If this happens to you, do not drive or use machinery.
- It is better to take with food to avoid an upset stomach.
- Your doctor may adjust your dose if you have liver or kidney disease.
- In case of overdose, tell your doctor immediately.
Moderate to severe pain
May with or without food.
Oral Moderate to severe pain Adult: 1-2 tab 6 hrly. Max: 8 tab/day. Max duration: 5 days. Hepatic impairment: Moderate: Increase dosing interval.... View More
Not recommended in child under 18 years of age.
Renal impairment: CrCl (ml/min) Dosage Recommendation 10-30 Increase dosing interva to 12 hr.ly <10 Not recommended.
Hypersensitivity to tramadol, paracetamol or opioids. Situations where opioid use may be contra-indicated (e.g. acute intoxication with alcohol, hypnoti... View More
Mode of Action
Tramadol is a centrally acting opioid analgesic which binds to mu-opioid receptors and weakly inhibits the reuptake of norepinephrine and serotonin. Par... View More
Patient w/ epilepsy controlled by treatment, risk of seizure, cranial trauma, biliary tract disorder, altered state of consciousness for unknown reasons... View More
Postural hypotension, resp depression, hepatotoxicity, Stevens-Johnson syndrome, toxic epidermal necrolysis, bradycardia, collapse, allergic reactions w... View More
Increased risk of seizures and serotonin syndrome w/ SSRIs, SNRIs, TCAs, and 5-HT agonists (e.g. sumatriptan). Increased CNS depression w/ barbiturates,... View More
Alternative brand for Sinergix
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More