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Misoclo 50/20050mg+200mcg

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General Pharmaceuticals Ltd.
Generic: Diclofenac Sodium + Misoprostol
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descriptionMedical Overview


Rheumatoid arthritis, Osteoarthritis, Joint and muscular pains


Swallow tablet whole, do not chew or crush Do not take with antacids

Adult Dose

Osteoarthritis 50 mg/200 mcg, 75mg/200mcg: 1 tab PO three times daily; not to exceed 200 mcg misoprostol/dose or 800 mcg/day Rheumatoid Arthritis 5... View More

Child Dose

Safety & efficacy not established


Diclofenac Sodium and Misoprostol combination is contraindicated in women who are pregnant because of the abortive property of the Misoprostol component... View More

Mode of Action

Diclofenac: Inhibits cyclooxygenase-1 (COX-1) & -2 (COX-2), thereby inhibiting prostaglandin synthesis; has anti-inflammatory, antipyresis, and analgesi... View More


Patients with an underlying condition such as inflammatory bowel disease or those in whom dehydration should be monitored carefully if Diclofenac Sodium... View More

Side Effect

>10% Rash including erythematous, rash macular and maculo-papular (18%),Pyrexia (15%),Urticaria (13%),Flushing (13%) 1-10% Hypertension (10%),Hyper... View More

Pregnancy Category Note

Pregnancy Category: X Lactation: Enters breast milk; use with caution


May increase serum levels of methotrexate. Concomitant use w/ other NSAIDs or anticoagulants (e.g. warfarin) is associated w/ higher risk of GI bleedin... View More

Alternative brand for Misoclo 50/200
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The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More