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Singlin0.5mg

Tablet
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Renata Limited
Generic: Repaglinide
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descriptionSafety Advices
AlcoholAlcohol
UNSAFE
It is unsafe to consume alcohol with Singlin.
PregnancyPregnancy
CONSULT YOUR DOCTOR
Singlin may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing... View More
BreastfeedingBreastfeeding
SAFE IF PRESCRIBED
Singlin is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby. Mon... View More
DrivingDriving
CAUTION
Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.
KidneyKidney
CAUTION
Singlin should be used with caution in patients with severe kidney disease. Dose adjustment of Singlin may be needed. Please consult your doctor.
LiverLiver
CAUTION
Singlin should be used with caution in patients with liver disease. Dose adjustment of Singlin may be needed. Please consult your doctor. Use of Singlin... View More
descriptionMedical Overview

Introduction

Singlin is used to lower blood sugar levels in adults with type 2 diabetes mellitus. It is usually prescribed along with other diabetes medicines to ach... View More

Uses of Singlin

  • Type 2 diabetes mellitus

Side effects of Singlin

Common
  • Joint pain
  • Dizziness
  • Back pain
  • Diarrhea
  • Flu-like symptoms
  • Upper respiratory tract infection

How to use Singlin

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Singlin is to be taken emp... View More

How Singlin works

Singlin is an anti-diabetic medication. It increases the amount of insulin released by the pancreas which prevents blood glucose from rising very high a... View More

What if you forget to take Singlin?

If you miss a dose of Singlin, skip it and continue with your normal schedule. Do not double the dose.

quick tipsQuick Tips
  • For best results, take Singlin 15 to 30 minutes before a meal.
  • You should continue to exercise regularly, eat a healthy diet, and take your other diabetes medicines along with Singlin
  • It may cause dizziness. Do not drive or do anything that requires mental focus until you know how Singlin affects you.
  • It may cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal.
  • Always carry some sugary food or fruit juice with you in case you experience hypoglycemic symptoms such as cold sweats, cool pale skin, tremor, and anxi... View More
  • Monitor your blood sugar levels regularly while you are taking this medicine.
  • Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
descriptionBrief Description

Indication

Type 2 DM

Administration

Take 15 minutes before meal; no more than 4 meals/day

Adult Dose

Oral Type 2 diabetes mellitus Adult: Usual initial dose: 0.5 mg before main meals. Initial doses of 1 or 2 mg may be used in patients who have had p... View More

Child Dose

Safety and efficacy not established

Renal Dose

Renal Impairment CrCl 40-80 mL/minute: No adjustments necessary CrCl 20-40 mL/minute: 0.5 mg with meals; titrate slowly and monitor CrCl < 20 mL/minu... View More

Contraindication

Diabetic ketoacidosis; severe hepatic impairment, type 1 diabetes; hypersensitivity. Lactation.

Mode of Action

Repaglinide stimulates release of insulin from pancreatic beta-cells by inhibiting K efflux via closure of ATP regulated K channels. This results in dep... View More

Precaution

Myocardial infarction, coma, trauma during surgery, elderly, malnourished and debilitated patients. Hepatic or severe renal impairment. Pregnancy.

Side Effect

Hypoglycaemia, nausea, diarrhoea, constipation, vomiting, dyspepsia, arthralgia, sinusitis, rhinitis, back pain; rash, pruritus, urticaria; visual distu... View More

Interaction

Cytochrome P450 3A4 inducers eg. rifampicin, barbiturates and carbamazepine may increase repaglinide metabolism. NSAIDs and other highly protein bound d... View More

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descriptionDisclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More