Bendamax25mg/vial
Injection
Beacon Pharmaceuticals Ltd.
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| Alcohol | CONSULT YOUR DOCTOR It is not known whether it is safe to consume alcohol with Bendamax. Please consult your doctor. |
| Pregnancy | CONSULT YOUR DOCTOR Bendamax is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in ... View More |
| Breastfeeding | UNSAFE Bendamax is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby. |
| Driving | CONSULT YOUR DOCTOR It is not known whether Bendamax alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and re... View More |
| Kidney | SAFE IF PRESCRIBED Bendamax is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Bendamax may not be needed in ... View More |
| Liver | CAUTION Bendamax should be used with caution in patients with liver disease. Dose adjustment of Bendamax may be needed. Please consult your doctor. |
Introduction
Bendamax is used to treat cancer of the lymphatic system such as Non-Hodgkin's Lymphoma (NHL). It may also be used to treat other types of cancer as det... View More
Uses of Bendamax
- Non-Hodgkin's lymphoma
- Blood cancer
- Multiple myeloma
Side effects of Bendamax
- Anemia (low number of red blood cells)
- Decreased white blood cell count
- Infection
- Fatigue
- Nausea
- Fever
- Vomiting
- Low blood platelets
- Mucosal inflammation
How to use Bendamax
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Bendamax works
Bendamax is an anti-cancer medication. It works by damaging the genetic material (DNA and RNA) of the cancer cells. This stops their growth and multipli... View More
What if you forget to take Bendamax?
If you miss a dose of Bendamax, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your ... View More
- Bendamax is given as an injection into vein under the supervision of a doctor.
Indication
Chronic lymphocytic leukaemia, Non-hodgkin's lymphoma, Multiple myeloma
Adult Dose
Intravenous Chronic lymphocytic leukaemia Adult: 100 mg/m2 infused over 30-60 min on days 1 and 2 of a 28-day cycle for up to 6 cycles. For severe... View More
Renal Dose
Renal Impairment Mild-to-moderate: Use caution CrCl <40 mL/min: Not recommended
Contraindication
Patient w/ history of hypersensitivity (e.g. anaphylaxis and anaphylactoid reactions); jaundice, severe bone marrow suppression, low leukocyte or platel... View More
Mode of Action
Bendamustine is an antineoplastic alkylating agent. It interferes w/ DNA replication and RNA transcription that leads to disruption of nucleic acid fun... View More
Precaution
Interrupt if severe infusion reactions Mild-mod renal impairment, mild hepatic impairment Possibility of anaphylactic/infusion reactions: severe i... View More
Side Effect
>10% Lymphopenia (68-99%),Leukopenia (61-94%; grade 3/4, 28-56%),Anemia (88-89%; grades 3/4 11-13%),Thrombocytopenia (77-86%; grade 3/4, 11-25%),,Neutr... View More
Pregnancy Category Note
Pregnancy There are no available data on use in pregnant women to evaluate for a drug-associated risk of major birth defects, miscarriage or adverse ma... View More
Interaction
May increase plasma levels w/ CYP1A2 inhibitors (e.g. ciprofloxacin, fluvoxamine). May reduce plasma levels w/ CYP1A2 inducers (e.g. omeprazole and toba... View More
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More