Retinol2LacIU

Indication

Vitamin A deficiency, Night blindness, Xerophthalmia

Administration

Should be taken with food.

Adult Dose

Oral Vitamin A deficiency Adult: For severe deficiency with corneal changes: 500,000 units daily for 3 days, followed by 50,000 units daily for 2 wk a... View More

Child Dose

Oral Vitamin A deficiency Child: In children with xerophthalmia: 5000 units/kg daily for 5 days or until recovery occurs.

Contraindication

Hypervitaminosis A; pregnancy (dose exceeding RDA).

Mode of Action

Vitamin A plays an essential role in the function of retina and is essential for growh and differentiation of epithelial tissue.

Precaution

Cholestatic jaundice; fat-malabsorption conditions. Monitor patients closely for toxicity. Liver impairment and children.

Side Effect

Hypervitaminosis A characterised by fatigue, irritability, anorexia, weight loss, vomiting and other GI disturbances, low-grade fever, hepatosplenomegal... View More

Interaction

Decreased absorption with neomycin. Increased risk of hypervitaminosis A with synthetic retinoids eg, acitretin, isotretinoin and tretinoin. Increased r... View More