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Uromitexan400mg/4ml

Injection
rx_reqRequire Prescription
Generic: Mesna Disulfide
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descriptionSafety Advices
AlcoholAlcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Uromitexan. Please consult your doctor.
PregnancyPregnancy
SAFE IF PRESCRIBED
Uromitexan is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, th... View More
BreastfeedingBreastfeeding
UNSAFE
Uromitexan is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
DrivingDriving
UNSAFE
Uromitexan may cause side effects which could affect your ability to drive. As patients undergoing treatment with Uromitexan may experience undesirable ... View More
KidneyKidney
CONSULT YOUR DOCTOR
There is limited information available on the use of Uromitexan in patients with kidney disease. Please consult your doctor.
LiverLiver
CONSULT YOUR DOCTOR
There is limited information available on the use of Uromitexan in patients with liver disease. Please consult your doctor.
descriptionMedical Overview

Introduction

Uromitexan is used to prevent ifosfamide-induced hemorrhagic cystitis. But, its not used to reduce the risk of blood in the urine due to other medical c... View More

Uses of Uromitexan

  • Ifosfamide-induced hemorrhagic cystitis

Side effects of Uromitexan

Common
  • Nausea
  • Headache
  • Lightheadedness
  • Lethargy
  • Abdominal pain
  • Flushing (sense of warmth in the face, ears, neck and trunk)
  • Diarrhea
  • Rash
  • Fever
  • Flu-like symptoms

How to use Uromitexan

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Uromitexan works

Uromitexan helps to reduce the risk of inflammation and bleeding in the bladder, who receive ifosfamide (a medicine used to treat cancer).

quick tipsQuick Tips
  • Drink at least 1 litre of fluid daily while you are receiving mesna.
  • Seek immediate medical attention if you experience severe allergic reactions like rash, itching, breathing difficulty, chest tightness, and swelling of ... View More
  • Do not drive or operate machinery as mesna may cause drowsiness, dizziness, blurred vision, or light headedness.
  • Tell your doctor if you are pregnant or planning to become pregnant or are breastfeeding.
  • You will be monitored for blood or protein in urine during the treatment of mesna.
  • Do not take if allergic to mesna or any of its ingredients (thiol containing compound)
descriptionBrief Description

Indication

Urothelial toxicity

Administration

IV Preparation Reconstitute w/ D5W, NS, dextrose/saline or LR to a final concentration of 20 mg/mL IV Administration IVP: bolus 15 min before ifosf... View More

Adult Dose

Intravenous Prophylaxis against urothelial toxicity With Ifosfamide 240 mg/sq.meter (if receiving 1.2 g/sq.meter ifosfamide dose) IVP 15 minutes befo... View More

Contraindication

Hypersensitivity to thiol-containing compounds.

Mode of Action

Mesna is used to prevent urothelial toxicity associated with oxazaphosphorine, ifosfamide or cyclophosphamide. It acts in the kidney; reacting with thio... View More

Precaution

Protective effect applies only to the urinary tract; pregnancy, lactation. Patients with auto-immune disorders. IV formulation may contain benzyl alcoho... View More

Side Effect

>10% Nausea (>50%),Vomiting (29%),Anorexia.Asthenia,Fatigue,Fever,Abdominal pain,Constipation,Anemia,Granulocytopenia,Leukopenia,Thrombocytopenia,Alope... View More

Interaction

Mesna is incompatible in vitro with cisplatin and nitrogen mustard.

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descriptionDisclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More