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Bortez 11mg/vial

Injection
rx_reqRequire Prescription
Beacon Pharmaceuticals Ltd.
Generic: Bortezomib
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descriptionSafety Advices
AlcoholAlcohol
UNSAFE
Bortez 1 may cause excessive drowsiness with alcohol.
PregnancyPregnancy
CONSULT YOUR DOCTOR
Bortez 1 is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in ... View More
BreastfeedingBreastfeeding
UNSAFE
Bortez 1 is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
DrivingDriving
UNSAFE
Bortez 1 may cause side effects which could affect your ability to drive. Bortez 1 might cause tiredness, dizziness, fainting, or blurred vision which m... View More
KidneyKidney
CAUTION
Bortez 1 should be used with caution in patients with severe kidney disease. Dose adjustment of Bortez 1 may be needed. Please consult your doctor. Limi... View More
LiverLiver
CAUTION
Bortez 1 should be used with caution in patients with liver disease. Dose adjustment of Bortez 1 may be needed. Please consult your doctor.
descriptionMedical Overview

Introduction

Bortez 1 is used in the treatment of multiple myeloma and mantle-cell lymphoma. It shows its working by stopping or slowing down the growth of cancer ce... View More

Uses of Bortez 1

  • Multiple myeloma
  • Mantle-cell lymphoma

Side effects of Bortez 1

Common
  • Low blood platelets
  • Fatigue
  • Peripheral neuropathy (tingling and numbness of feet and hand)
  • Psychiatric disturbances
  • Nausea
  • Vomiting
  • Loss of appetite
  • Fever
  • Anemia (low number of red blood cells)
  • Diarrhea
  • Decreased appetite
  • Decreased white blood cell count (neutrophils)
  • Constipation

How to use Bortez 1

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Bortez 1 works

Bortez 1 is an anti-cancer medication. It works by blocking or slowing the breakdown of proteins in cells. As a result, there is an increase in a number... View More

What if you forget to take Bortez 1?

If you miss a dose of Bortez 1, please consult your doctor.

quick tipsQuick Tips
  • Before taking bortezomib, consult your doctor if you have any of the following disease conditions: disease of liver, kidney, heart or infections like fe... View More
  • Drink plenty of fluids every day during your treatment with bortezomib.
  • Tell your doctor if you are or planning to become pregnant or are breastfeeding.
  • Consult your doctor if you have signs of serious brain infection such as memory loss, trouble in thinking, difficulty with walking or loss of vision.
  • Do not drive or operate machinery after taking bortezomib as it may cause tiredness, dizziness, fainting or blurred vision.
descriptionBrief Description

Indication

Mantle Cell Lymphoma, Multiple Myeloma,

Administration

IV or SC Preparation Reconstitute vial with 0.9% NaCl IV administration: Add 3.5 mL to vial for final concentration of 1 mg/mL SC administration: 2.5... View More

Adult Dose

Mantle Cell Lymphoma Indicated for treatment of patients with mantle cell lymphoma as first-line in previously untreated patients or those who have rel... View More

Contraindication

Hypersensitivity. Child. Pregnancy and lactation.

Mode of Action

Bortezomib is a reversible inhibitor of the chymotrypsin-like activity of the 26-S proteasome. It prevents targeted proteolysis that affects multiple si... View More

Precaution

Hepatic or renal impairment; history of syncope, orthostatic hypotension; dehydration. Impairs ability to drive or operate machinery. Monitor for sympto... View More

Side Effect

>10% Asthenia (61-65%) Nausea (61-65%) Diarrhea (51-55%) Anorexia (41-45%) Constipation (41-45%) Thrombocytopenia (41-45%) Peripheral neuropathy ... View More

Pregnancy Category Note

Pregnancy Based on mechanism of action and findings in animals, therapy can cause fetal harm when administered to a pregnant woman; there are no stud... View More

Interaction

Concurrent use of amiodarone, antivirals, isoniazid, nitrofurantoin, statins may increase the chance of peripheral neuropathy. Concurrent use of antihyp... View More

descriptionDisclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More