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Popular Pharmaceuticals PLC
Generic: Lidocaine + Prilocaine topical
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descriptionSafety Advices
No interaction found/established
Topican is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there... View More
Topican is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
No interaction found/established
No interaction found/established
No interaction found/established
descriptionMedical Overview


Topican is a combination of two local anesthetic medicines, that helps to numb the area where it is applied. It is used on normal or unbroken skin to pr... View More

Uses of Topican

  • Local anesthesia (Numb tissues in a specific area)

Side effects of Topican

  • Application site reactions (burning, irritation, itching and redness)
  • Rash

How to use Topican

This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and ... View More

How Topican works

Topican is a combination of two medicines: Prilocaine and Lidocaine/Lignocaine. It works by blocking pain signals from the nerves of the affected area t... View More

quick tipsQuick Tips
  • Topican must be applied over intact skin and cover with treated area with dressing.
  • Do not apply it to broken or infected areas of skin, face, eyes or eyelids unless specifically instructed by your doctor.
  • Wash your hands properly with soap before and after applying the medicine.
  • Avoid contact with the eyes, mouth, nose or any mucous membrane and rinse thoroughly in case of accidental contact or seek medical help in case of inges... View More
  • It may cause minor burning, stinging, or irritation when applied. Inform your doctor if this does not go away.
descriptionBrief Description


Local anaesthesia


Apply a thick layer to intact skin and cover with occlusive dressing. Gently squeeze cream out of the tube as a narrow strip that is 1.5 inches long ... View More

Adult Dose

Topical Dermal Procedures Minor dermatological procedures (e.g. IV cannulation or venipuncture): Cream: Apply 2.5 g over 20-25 cm² of skin surface ... View More

Child Dose

Local Anesthetic Procedures Cream Neonates (gestation age <37 weeks): Use not recommended <12 months: Do not use if receiving treatment with methemog... View More


Neonates with gestational age <37 wk. Infants <12 mth of age who are receiving treatment with methaemoglobin-inducing agents or children who are receivi... View More

Mode of Action

Lidocaine and prilocaine are local anaesthetic agents of the amide type. Both work by stabilising the neuronal membranes and inhibiting the ionic fluxes... View More


Caution when used over large areas and leaving on for >2 hr. Severe hepatic impairment. Caution when used in patients who are receiving class I and III ... View More

Side Effect

>10% Pallor/blanching (37%),Application site erythema/pain (30%),Genital mucous membrane burning sensation (17%),Oral cavity, periodontal formulation (... View More


Increased risk of toxicity when used with drugs that are known to cause methaemoglobinaemia. Concurrent use with class III antiarrhythmics may lead to a... View More


The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More

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