Paclitor100mg/vial
Injection
Eskayef Pharmaceuticals Ltd.
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| Alcohol | UNSAFE It is unsafe to consume alcohol with Paclitor. |
| Pregnancy | CONSULT YOUR DOCTOR Paclitor is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in ... View More |
| Breastfeeding | UNSAFE Paclitor is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby. |
| Driving | UNSAFE Paclitor may cause side effects which could affect your ability to drive.
As there is no reason why you cannot continue driving between courses of Pacli... View More |
| Kidney | SAFE IF PRESCRIBED Paclitor is safe to use in patients with kidney disease. No dose adjustment of Paclitor is recommended.
However, talk to your doctor if you have any und... View More |
| Liver | CAUTION Paclitor should be used with caution in patients with liver disease. Dose adjustment of Paclitor may be needed. Please consult your doctor.
Use of Pacli... View More |
Introduction
Paclitor is an anti-cancer medication used for the treatment of breast cancer, pancreatic cancer and non-small cell lung cancer. It is given as an inje... View More
Uses of Paclitor
- Breast cancer
- Non-small cell lung cancer
- Pancreatic cancer
Side effects of Paclitor
- Nausea
- Vomiting
- Weakness
- Low blood platelets
- Rash
- Upper respiratory tract infection
- Urinary tract infection
- Bleeding
- Anemia (low number of red blood cells)
- Flushing (sense of warmth in the face, ears, neck and trunk)
- Hair loss
- Decreased blood pressure
- Peripheral neuropathy (tingling and numbness of feet and hand)
- Diarrhea
- Decreased white blood cell count (neutrophils)
How to use Paclitor
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Paclitor works
Paclitor is an anticancer medication. It works by interfering with the microtubule structures which help the cancer cells to divide and multiply. This s... View More
- Paclitor is an anti-cancer medication used for the treatment of breast cancer, pancreatic cancer, and non-small cell lung cancer.
- It is given as an intravenous (IV) injection into your vein, usually over 1 hour and every three weeks.
- Do not take Paclitor if you are pregnant or breastfeeding. Use reliable methods of contraception to prevent pregnancy while taking this medicine.
- Your doctor may get regular blood tests done to monitor your blood cells and liver function during treatment with this medicine.
- Inform your doctor if you notice unexplained bruising or bleeding, sore throat, mouth ulcers, high temperature (fever) or other signs of infection.
- Talk to your doctor if you have sudden weight gain or if you have swelling in your arms and legs that doesn't go away.
Indication
Ovarian carcinoma, Breast cancer, Lung cancer, Kaposi's sarcoma
Administration
Reconstitution: Paclitaxel must be diluted before infusion. It can be diluted in 0.9% sodium chloride inj, 5% dextrose inj, 5% dextrose and 0.9% sodium ... View More
Adult Dose
Intravenous Ovarian carcinoma Adult: Primary treatment (in combination with cisplatin or carboplatin): 135 mg/m2 infused over 24 hr followed by cispla... View More
Child Dose
Safety and efficacy not established
Contraindication
History of hypersensitivity (especially macrogol glycerol ricinolate). Patients with baseline neutropenia of <1500 cells/mm3 (<1000 cells/mm3 for kaposi... View More
Mode of Action
Paclitaxel promotes microtubule formation by enhancing the action of tubulin dimers, stabilising existing microtubules and preventing their disassembly,... View More
Precaution
Bone marrow suppression during therapy. Monitor cardiac function if conduction abnormalities result. Premedicaton (with corticosteroid, antihistamine an... View More
Side Effect
>10% Neutropenia (78-100%),Alopecia (55-96%),Anemia (47-96%),Arthralgia/myalgia (93%),Diarrhea (90%),Leukopenia (90%),Nausea/vomiting (9-88%),Opportuni... View More
Interaction
Myelosuppression was more profound when given after cisplatin than with the alternate sequence (e.g., paclitaxel before cisplatin). CYP2C8 inducers e.g.... View More
Alternative brand for Paclitor
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More