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Servizid300mg

Tablet
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Novartis (Bangladesh) Ltd.
Generic: Isoniazid
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descriptionSafety Advices
AlcoholAlcohol
UNSAFE
Consuming alcohol while taking Servizid may cause symptoms such as flushing, increased heart beat, nausea, thirst, chest pain and low blood pressure (Di... View More
PregnancyPregnancy
CONSULT YOUR DOCTOR
Servizid may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developin... View More
BreastfeedingBreastfeeding
SAFE IF PRESCRIBED
Servizid is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not h... View More
DrivingDriving
UNSAFE
Servizid may cause side effects which could affect your ability to drive. Servizid can cause fits, mental health problems and optic neuritis (inflammati... View More
KidneyKidney
SAFE IF PRESCRIBED
Servizid is safe to use in patients with kidney disease. No dose adjustment of Servizid is recommended. However, talk to your doctor if you have any und... View More
LiverLiver
CAUTION
Servizid should be used with caution in patients with liver disease. Dose adjustment of Servizid may be needed. Please consult your doctor. Use of Servi... View More
descriptionMedical Overview

Introduction

Servizid is an antibiotic used for the treatment and prevention of tuberculosis (TB) and inactive (latent) TB (a serious infection caused by bacteria th... View More

Uses of Servizid

  • Tuberculosis (TB)

Side effects of Servizid

Common
  • Peripheral neuropathy (tingling and numbness of feet and hand)
  • Increased liver enzymes
  • Hepatitis (viral infection of liver)
  • Jaundice

How to use Servizid

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Servizid is to be taken em... View More

How Servizid works

Servizid is an antibiotic. It works by killing the bacteria that causes tuberculosis.

What if you forget to take Servizid?

If you miss a dose of Servizid, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your ... View More

quick tipsQuick Tips
  • Your doctor has prescribed Servizid to cure your infection and improve symptoms.
  • It is best taken on an empty stomach.
  • You must also take a vitamin B6 supplement while on Servizid.
  • Tell your doctor immediately if you experience vision changes, loss of appetite, tiredness, stomach pain, nausea or vomiting, yellow skin or eyes or dar... View More
descriptionBrief Description

Indication

Tuberculosis

Administration

Should be taken on an empty stomach. Best taken on an empty stomach 1 hr before or 2 hr after meals. May be taken w/ meals to reduce GI discomfort.

Adult Dose

Oral Active Tuberculosis Disease 5 mg/kg PO qDay, not to exceed 300 mg qDay 15 mg/kg PO up; not to exceed 900 mg 1-3 times/week Used in multi-dru... View More

Child Dose

Active Tuberculosis Disease 10-15 mg/kg PO qDay; not to exceed 300 mg/day OR 20-30 mg/kg (up to 900 mg) 2 times/week Used in multi-drug regimen ... View More

Renal Dose

Renal impairment: Severe: Dose reduction may be needed.

Contraindication

Acute liver disease or history of hepatic damage during INH therapy; hypersensitivity.

Mode of Action

Isoniazid inhibits the synthesis of mycoloic acids in susceptible bacteria which results in loss of acid-fastness and disruption of bacterial cell wall.... View More

Precaution

Renal or hepatic impairment; convulsive disorders; history of psychosis; patients at risk of neuropathy or pyridoxine deficiency eg, diabetic, alcoholic... View More

Side Effect

>10% Mild incr LFTs (10-20%),Peripheral neuropathy (dose-related incidence, 10-20% incidence with 10 mg/kg/d) Loss of appetite,Nausea,Vomiting,Stomach... View More

Interaction

Inhibit the hepatic metabolism of antiepileptics (e.g. carbamazepine, ethosuximide, primidone, phenytoin), benzodiazepines (e.g. diazepam, triazolam), c... View More

descriptionDisclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More