Introduction
Uricon CR is used in the treatment of overactive bladder. It relieves urinary symptoms like frequent urination, urgent need to urinate and inability to control urination.
Uricon CR is advised to take it in a dose and duration as per prescription. It should be taken in an empty stomach at least an hour before having a meal. Swallow the medicine as a whole without crushing or chewing it. You should not stop taking the medicine without consulting the doctor as it may lead to the worsening of your symptoms. The course of the treatment should be completed for better efficacy of the medicine.
Some common side effects of this medicine are dry mouth, constipation, diarrhea, headache, etc. To cope up with the side effects, you must drink plenty of water. It may also make you feel dizzy or sleepy or experience blurry vision, so it advised not to drive or do anything requiring concentration until you know how it affects you. Consumption of alcohol must be avoided as it can aggravate the side effects. If any of the side effects bother you or persist, consult the doctor without delay.
Before receiving the treatment, inform your doctor if you are on any medication for any other health condition. If you are pregnant or breastfeeding, tell your doctor prior to the treatment.
Uses of Uricon CR
- Overactive bladder (OAB) symptoms
Side effects of Uricon CR
Common
- Dryness in mouth
- Constipation
- Diarrhea
- Blurred vision
- Dry skin
- Dizziness
- Headache
- Sleepiness
How to use Uricon CR
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Uricon CR is to be taken empty stomach.
How Uricon CR works
Uricon CR is an antimuscarinic. It works by relaxing muscles of the urinary bladder and prevents frequent, urgent or uncontrolled urination.
What if you forget to take Uricon CR?
If you miss a dose of Uricon CR, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Indication
Overactive bladder
Administration
May be taken with or without food.
Adult Dose
Oral
Overactive bladder
Adult: As extended-release preparation: Initially, 5 mg once daily increased by 5 mg every wk if necessary to max 30 mg daily.
Child Dose
Oral
Detrusor Overactivity, Nocturnal enuresis
Bladder overactivity associated with a neurologic condition (eg, spina bifida)
Child >6 years (extended-release): 5 mg/day PO initially; may be increased by 5 mg/day at weekly intervals; not to exceed 20 mg/day
Contraindication
GI obstruction or atrophy, severe toxic megacolon, significant bladder outflow obstruction, glaucoma, urinary retention.
Mode of Action
Oxybutynin exerts direct antispasmodic effect on the smooth muscle by inhibiting the muscarinic action of acetylcholine. It exhibits moderate anticholinergic effect, but has potent antispasmodic effects on urinary smooth muscle.
Precaution
Elderly; hepatic or renal impairment; neuropathy; hyperthyroidism; prostatic hyperplasia; hiatus hernia; cardiac disease, reflux oesophagitis, ulcerative colitis, myasthenia gravis; pregnancy and lactation. High environmental temperature might cause heat prostration (fever with heat stroke due to decreased sweating).
Lactation: Unknown; use with caution
Side Effect
>10%
Dry mouth (21-71%),Constipation (7-15%),Somnolence (2-14%),Nausea (2-12%)
1-10%
Asthenia (6-10%),Dizziness (6-10%),Headache (6-10%),Blurred vision (6-10%),Dry eyes (6-10%),Diarrhea (6-10%),Nausea (6-10%),Pain (6-10%),Rhinitis (6-10%)
<1%
Anorexia,Fluid retention,Hot flush,Dysphonia,Dysphagia,Frequent bowel movements,Chest discomfort,Thirst
Frequency Not Defined
Cycloplegia,Impairment of mental alertness,Memory impairment,Mydriasis,Tachycardia,QT prolongation
Interaction
Co-administration with other anticholinergic drugs may cause undesirable increased anticholinergic effects. Additive sedation with CNS depressants and alcohol. Concentration may be increased by CYP3A4 inhibitirs (e.g. imidazole antifungals, macrolide antibiotics).