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Metalyse50mg

Injection
rx_reqRequire Prescription
Radiant Pharmaceuticals Ltd.
Generic: Tenecteplase
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descriptionSafety Advices
AlcoholAlcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Metalyse. Please consult your doctor.
PregnancyPregnancy
CONSULT YOUR DOCTOR
Metalyse may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developin... View More
BreastfeedingBreastfeeding
CAUTION
Metalyse should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is e... View More
DrivingDriving
NOT RELEVANT
Not relevant, as Metalyse is intended for use in hospitalised patients.
KidneyKidney
CONSULT YOUR DOCTOR
There is limited information available on the use of Metalyse in patients with kidney disease. Please consult your doctor.
LiverLiver
CONSULT YOUR DOCTOR
There is limited information available on the use of Metalyse in patients with liver disease. Please consult your doctor.
descriptionMedical Overview

Introduction

Metalyse belongs to a group of medicines called thrombolytic agents. It is used in the emergency treatment of heart attack. It helps to dissolve blood c... View More

Uses of Metalyse

  • Heart attack

Side effects of Metalyse

Common
  • Injection site bleeding
  • Nosebleeds
  • Blood in stool
  • Blood in urine
  • Gastrointestinal bleeding

How to use Metalyse

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Metalyse works

Metalyse is a thrombolytic medication. It works by dissolving the harmful blood clots in the blood vessels. This restores the blood flow to the affected... View More

quick tipsQuick Tips
  • Metalyse is used to treat myocardial infarctions (heart attacks) as soon as possible (usually within 12 hours) after the onset of symptoms.
  • It is given as an injection into the vein under the supervision of a doctor.
  • It may increase your risk of bleeding. Inform your doctor immediately if you notice bleeding at the injection site, nose bleed, and blood in urine.
  • Continue with your diet and exercise along with previously prescribed medications for heart attack.
descriptionBrief Description

Indication

Acute myocardial infarction

Administration

IV Preparation Add 10 mL SWI to a 50 mg vial using TwinPak® device directing stream of diluent into powder. If foaming (usually slight) occurs, leave v... View More

Adult Dose

Intravenous Acute myocardial infarction Adult: 30-50 mg as a single bolus dose over 5-10 sec as soon as possible after the onset of symptoms. The dose... View More

Contraindication

Patients at risk of cerebral bleeding including severe hypertension, history of stroke, intracranial or intraspinal surgery or trauma within 2 mth, arte... View More

Mode of Action

Tenecteplase is a biosynthetic form of the enzyme human tissue-type plasminogen activator (t-PA). It is a fibrin-specific thrombolytic, converts plasmin... View More

Precaution

Patients with increased risk of bleeding. Recent history of GI or genitourinary bleed, recent major surgery, previous puncture of noncompressible vessel... View More

Side Effect

>10% Minor bleeding (22%) Frequency Not Defined Reperfusion arrhythmias MI Fever Nausea Vomiting Cholesterol embolization Allergic reaction

Interaction

Increased risk of haemorrhage with heparin, oral anticoagulants, antiplatelet drugs and other drugs that can affect platelet function.

descriptionDisclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More