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Revolade25mg

Tablet
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GlaxoSmithKline
Generic: Eltrombopag Olamine
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descriptionSafety Advices
AlcoholAlcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Revolade. Please consult your doctor.
PregnancyPregnancy
CONSULT YOUR DOCTOR
Revolade may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developin... View More
BreastfeedingBreastfeeding
CONSULT YOUR DOCTOR
Revolade is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
DrivingDriving
UNSAFE
Revolade may cause side effects which could affect your ability to drive. Revolade can make you dizzy and have other side effects that make you less ale... View More
KidneyKidney
SAFE IF PRESCRIBED
Revolade is safe to use in patients with kidney disease. No dose adjustment of Revolade is recommended. However, inform your doctor if you have a kidney... View More
LiverLiver
CAUTION
Revolade should be used with caution in patients with liver disease. Dose adjustment of Revolade may be needed. Please consult your doctor.
descriptionMedical Overview

Introduction

Revolade is used to treat low platelet count due to chronic immune (idiopathic) thrombocytopenic purpura (ITP) or chronic hepatitis C virus (HCV) infect... View More

Uses of Revolade

  • Low platelet count due to ITP or HCV infection

Side effects of Revolade

Common
  • Nausea
  • Diarrhea
  • Upper respiratory tract infection
  • Vomiting
  • Increased liver enzymes
  • Muscle pain
  • Urinary tract infection

How to use Revolade

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Revolade is to be taken em... View More

How Revolade works

Revolade is a thrombopoietin agonist. It works by stimulating the formation of new platelets in the blood. Platelets help to reduce or prevent bleeding.... View More

What if you forget to take Revolade?

If you miss a dose of Revolade, skip it and continue with your normal schedule. Do not double the dose.

quick tipsQuick Tips
  • Take Revolade on an empty stomach, either 1 hour before or 2 hours after meals.
  • Take Revolade at least 2 hours before or 4 hours after eating dairy products and calcium-fortified juices.
descriptionBrief Description

Indication

Adult chronic immune (idiopathic) thrombocytopenic purpura (ITP), Hepatitis C Virus (HCV) related, Thrombocytopenia, Aplastic anemia

Administration

Should be taken on an empty stomach: Take at least 4 hr before or after antacids, dairy products or other Ca-containing food products or mineral supplem... View More

Adult Dose

Adult Chronic ITP: Initial dose 50 mg once daily. Adjust to maintain platelet count greater than or equal to 50×109 /L ... View More

Child Dose

Child 6 years or older Chronic ITP: Initial dose 50 mg once daily. Child 1 to 5 year The initial dose is 25 mg once daily. Adjust to maintain pl... View More

Renal Dose

Renal Impairment: No dose adjustment is necessary in ITP patients with renal impairment.

Contraindication

Eltrombopag is contraindicated in patients with severe hepatic impairment and who are hypersensitive to any of its excipients.

Mode of Action

Small-molecule thrombopoietin (TPO)-receptor agonist that interacts with human TPO receptor transmembrane domain of human TPO-receptor & initiates signa... View More

Precaution

Regularly monitor clinical haematology, platelet counts & serum liver test throughout therapy. Renal & hepatic impairment; hepatic disease. Thrombotic/t... View More

Side Effect

Most common adverse reactions are nausea diarrhea, upper respiratory tract infection, increased ALT, mayalgia, urinanry tract infection, fatigue, headac... View More

Pregnancy Category Note

Pregnancy Available data from published case reports and postmarketing experience with use in pregnant women are insufficient to assess any drug-associ... View More

Interaction

Increased plasma Cmax & AUC of HMG-CoA reductase inhibitors. Caution w/ methotrexate, topotecan. Increased conc w/ fluvoxamine; decreased conc w/ rifamp... View More

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descriptionDisclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More