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Amotrex 400400mg

Tablet
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ACI Limited
Generic: Metronidazole
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descriptionSafety Advices
AlcoholAlcohol
UNSAFE
Consuming alcohol while taking Amotrex 400 may cause symptoms such as flushing, increased heart beat, nausea, thirst, chest pain and low blood pressure ... View More
PregnancyPregnancy
SAFE IF PRESCRIBED
Amotrex 400 is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, t... View More
BreastfeedingBreastfeeding
CAUTION
Amotrex 400 should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug i... View More
DrivingDriving
UNSAFE
Amotrex 400 may cause side effects which could affect your ability to drive. Amotrex 400 may make you feel sleepy, dizzy, confused. You may have halluci... View More
KidneyKidney
SAFE IF PRESCRIBED
Amotrex 400 is safe to use in patients with kidney disease. No dose adjustment of Amotrex 400 is recommended. Patients undergoing kidney dialysis should... View More
LiverLiver
CAUTION
Amotrex 400 should be used with caution in patients with liver disease. Dose adjustment of Amotrex 400 may be needed. Please consult your doctor.
descriptionMedical Overview

Introduction

Amotrex 400 is an antibiotic medicine that helps your body fight infections caused by bacteria and parasites. It is used to treat infections of the live... View More

Uses of Amotrex 400

  • Bacterial infections
  • Parasitic infections

Side effects of Amotrex 400

Common
  • Headache
  • Dryness in mouth
  • Nausea
  • Metallic taste

How to use Amotrex 400

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Amotrex 400 is to be taken... View More

How Amotrex 400 works

Amotrex 400 is an antibiotic. It kills the bacteria and other microorganisms that cause infections by damaging their DNA.

What if you forget to take Amotrex 400?

If you miss a dose of Amotrex 400, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to yo... View More

quick tipsQuick Tips
  • Amotrex 400 treats infections caused by bacteria and parasites.
  • It may cause side effects like nausea, stomach upset, and a metallic taste in the mouth.
  • Amotrex 400 used in a high dose or for a prolonged time increases the risk of side effects such as nerve damage. Take it only as prescribed by your doct... View More
  • Do not drink alcohol during or for 2-3 days after treatment with this medicine. You may develop nausea, vomiting, flushing and headache.
  • Inform your doctor if you have liver disease. Your dose may need to be adjusted in severe liver disease.
descriptionBrief Description

Indication

Pneumonia, Giardiasis, Peptic ulcer disease, Peritonitis, H. pylori infection, Rosacea, Septicemia, Endometritis, Aspiration pneumonia, Lung abscess, Em... View More

Administration

Susp: Should be taken on an empty stomach. Take at least 1 hr before meals. Tab: Should be taken with food. Reconstitution: Add 4.4 mL of sterile or... View More

Adult Dose

Oral Child: PO 30–50 mg/kg/day q8h Amoebiasis Adult: 800 mg tid for 5 days (intestinal infection); 5-10 days (extra-intestinal infection). Max: 2.4... View More

Child Dose

Oral Amoebiasis Child: 1-3 yr 100-200 mg tid; >3-7 yr 100-200 mg 4 times daily; >7-10 yr 200-400 mg tid. Doses are given for 5-10 days. Trichom... View More

Contraindication

History of hypersensitivity to metronidazole or other nitroimidazole derivatives. Pregnancy (1st trimester) and lactation.

Mode of Action

Metronidazole is converted to reduction products that interact w/ DNA to cause destruction of helical DNA structure and strand leading to a protein synt... View More

Precaution

Patients with CNS diseases; discontinue IV therapy if abnormal neurologic symptoms occur. History of seizure disorder. Evidence or a history of blood dy... View More

Side Effect

GI disturbances e.g. nausea, unpleasant metallic taste, vomiting, diarrhoea or constipation. Furred tongue, glossitis, and stomatitis due to overgrowth ... View More

Interaction

Concurrent use w/ disulfiram may produce psychotic reactions. May potentiate the effect of oral anticoagulants. May increase risk of lithium toxicity. M... View More

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descriptionDisclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More