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Trastunix150mg/vial

Injection
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Beacon Pharmaceuticals Ltd.
Generic: Trastuzumab
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descriptionSafety Advices
AlcoholAlcohol
UNSAFE
Trastunix may cause excessive drowsiness with alcohol.
PregnancyPregnancy
CONSULT YOUR DOCTOR
Trastunix is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in... View More
BreastfeedingBreastfeeding
CONSULT YOUR DOCTOR
Trastunix is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
DrivingDriving
CONSULT YOUR DOCTOR
It is not known whether Trastunix alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and r... View More
KidneyKidney
SAFE IF PRESCRIBED
Trastunix is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Trastunix may not be needed i... View More
LiverLiver
CONSULT YOUR DOCTOR
There is limited information available on the use of Trastunix in patients with liver disease. Please consult your doctor.
descriptionMedical Overview

Introduction

Trastunix is used in the treatment of breast and stomach cancer. It works by killing the cancer cells by inhibiting HER2 (human epidermal growth factor ... View More

Uses of Trastunix

  • Breast cancer
  • Stomach cancer

Side effects of Trastunix

Common
  • Anemia (low number of red blood cells)
  • Chills
  • Common cold
  • Cough
  • Decreased blood cells (red cells, white cells, and platelets)
  • Diarrhea
  • Fatigue
  • Fever
  • Headache
  • Heart failure
  • Infection
  • Insomnia (difficulty in sleeping)
  • Mucosal inflammation
  • Nausea
  • Rash
  • Stomatitis (Inflammation of the mouth)
  • Taste change
  • Upper respiratory tract infection
  • Weight loss

How to use Trastunix

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Trastunix works

Trastunix is a recombinant IgG1 monoclonal antibody. It works against the HER2 (human epidermal growth factor receptor protein) receptors which are resp... View More

What if you forget to take Trastunix?

If you miss a dose of Trastunix, please consult your doctor.

quick tipsQuick Tips
  • It is given as an injection into your vein or under the skin, usually over 1 hour.
  • Use effective contraception method to prevent pregnancy while taking this medicine and for 7 months after you stop the treatment.
  • Your doctor will monitor your heart regularly while taking this medicine. Inform your doctor if you notice symptoms such as breathlessness, cough, shive... View More
  • Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
descriptionBrief Description

Indication

Breast cancer, Gastric cancer

Administration

IV Administration Not for IV push or bolus administration Administer initial IV infusion over 90 min Subsequent weekly IV infusions may be administer... View More

Adult Dose

Intravenous Breast Cancer Adjuvant treatment Indicated for adjuvant treatment of HER-2 overexpressing breast cancer Administer during and following ... View More

Child Dose

Safety and efficacy not established

Contraindication

Lactation (start only 6 mth after last dose of drug). Do not admin by rapid IV or bolus inj.

Mode of Action

Trastuzumab, a monoclonal antibody, has action directed against a cell surface protein produced by human epidermal growth factor receptor 2 (HER2). It i... View More

Precaution

Patient w/ pre-existing CV and pulmonary disease; extensive pulmonary tumour involvement. Pregnancy and lactation. Monitoring Parameters Monitor cardiac... View More

Side Effect

>10% Pain (47%),Asthenia (42%),Fever (36%),Nausea (33%),Chills (32%),Cough (26%),Headache (26%),Diarrhea (25%),Vomiting (23%),Abdominal pain (22%),Back... View More

Interaction

Increased risk of severe cardiotoxicity with anthracyclines. Increased risk of leukopenia and anaemia in combination chemotherapy (e.g. paclitaxel). Pac... View More

descriptionDisclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More