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Tazobac 4.54gm+0.5gm/vial

Injection
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ACI Limited
Generic: Piperacillin + Tazobactam
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descriptionSafety Advices
AlcoholAlcohol
SAFE
Consuming alcohol with Tazobac 4.5 does not cause any harmful side effects.
PregnancyPregnancy
SAFE IF PRESCRIBED
Tazobac 4.5 is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, t... View More
BreastfeedingBreastfeeding
SAFE IF PRESCRIBED
Tazobac 4.5 is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is no... View More
DrivingDriving
CONSULT YOUR DOCTOR
It is not known whether Tazobac 4.5 alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and... View More
KidneyKidney
CAUTION
Tazobac 4.5 should be used with caution in patients with kidney disease. Dose adjustment of Tazobac 4.5 may be needed. Please consult your doctor.
LiverLiver
SAFE IF PRESCRIBED
Tazobac 4.5 is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Tazobac 4.5 may not be neede... View More
descriptionMedical Overview

Introduction

Tazobac 4.5 is a combination of two antibiotics. It is used to treat various types of bacterial infections. It fights against the infection by killing t... View More

Uses of Tazobac 4.5

  • Bacterial infections

Side effects of Tazobac 4.5

Common
  • Nausea
  • Vomiting
  • Diarrhea
  • Rash
  • Allergic reaction

How to use Tazobac 4.5

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Tazobac 4.5 works

Tazobac 4.5 is a combination of two medicines: Piperacillin and Tazobactum. Piperacillin is an antibiotic. It works by preventing the formation of the b... View More

quick tipsQuick Tips
  • You have been prescribed this combination medicine to treat bacterial infections even if they have developed resistance.
  • Finish the prescribed course, even if you start to feel better. Stopping it early may make the infection come back and harder to treat.
  • Diarrhea may occur as a side effect. Taking probiotics along with Tazobac 4.5 may help. Talk to your doctor if you notice bloody stools or develop abdom... View More
  • Stop taking Tazobac 4.5 and inform your doctor immediately if you develop an itchy rash, swelling of the face, throat or tongue or breathing difficultie... View More
descriptionBrief Description

Indication

Septicaemia, Nosocomial pneumonia

Administration

Reconstitution Reconstitute initially (2.25 g in 10 mL, 4.5 g in 20 mL) w/ water for inj, glucose 5% or NaCl 0.9%, then further dilute to 50-150 mL w/ ... View More

Adult Dose

Intravenous Nosocomial pneumonia Adult: Each vial contains 4.5 g (piperacillin 4 g and tazobactam 0.5 g): 4.5 g 6 hrly for 5-14 days by infusion over ... View More

Child Dose

Intravenous Child: Usually <40 kg: 240–300 mg PIP/kg/day 8 hourly Alternatively Nosocomial pneumonia Child: 2-12 yr 90 mg/kg (piperacillin 80 mg/k... View More

Renal Dose

Renal impairment: Haemodialysis patients: 2.25 g 12 hrly; additional dose of 0.75 g after each dialysis session. CAPD: 2.25 g 12 hrly. CrCl (ml/min) Do... View More

Contraindication

Hypersensitivity.

Mode of Action

Piperacillin has an antimicrobial activity against a wide range of gm-ve organisms including K. pneumoniae, P. aeruginosa, Enterobacteriaceae and agains... View More

Precaution

Pregnancy and lactation, pseudomembranous colitis. Assess hematopoietic function periodically. Perform periodic electrolyte determinations in patients w... View More

Side Effect

>10% Diarrhea (7-11%) 1-10% Constipation (1-8%),Headache (1-8%),Insomnia (4-7%),Nausea (2-7%),Fever (2-5%),Oral candidiasis (2-4%),Rash (2-4%),Vomi... View More

Interaction

Interacts w/ high doses of heparin, oral anticoagulants or other drugs that affect blood coagulation or thrombocyte function. Prolongs the neuromuscular... View More

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descriptionDisclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More