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Oramet Plus500mg+2mg

Tablet
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Drug International Ltd.
Generic: Metformin Hydrochloride + Rosiglitazone
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descriptionSafety Advices
AlcoholAlcohol
UNSAFE
It is unsafe to consume alcohol with Oramet Plus.
PregnancyPregnancy
CONSULT YOUR DOCTOR
Oramet Plus may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the develo... View More
BreastfeedingBreastfeeding
CONSULT YOUR DOCTOR
Information regarding the use of Oramet Plus during breastfeeding is not available. Please consult your doctor.
DrivingDriving
CAUTION
Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.
KidneyKidney
CAUTION
Oramet Plus should be used with caution in patients with kidney disease. Dose adjustment of Oramet Plus may be needed. Please consult your doctor. Use o... View More
LiverLiver
CAUTION
Oramet Plus should be used with caution in patients with liver disease. Dose adjustment of Oramet Plus may be needed. Please consult your doctor. Oramet... View More
descriptionMedical Overview

Introduction

Oramet Plus is a combination medicine that helps control blood sugar levels. This medicine is used together with diet and exercise to improve blood suga... View More

Uses of Oramet Plus

  • Type 2 diabetes mellitus

Side effects of Oramet Plus

Common
  • Nausea
  • Loss of appetite
  • Taste change
  • Stomach pain
  • Diarrhea
  • Edema (swelling)
  • Weight gain
  • Bone fracture
  • Blurred vision
  • Respiratory tract infection

How to use Oramet Plus

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Oramet Plus is to be taken... View More

How Oramet Plus works

Oramet Plus is a combination of two antidiabetic medicines: Rosiglitazone and Metformin. Rosiglitazone is a thiazolidinedione which works by increasing ... View More

quick tipsQuick Tips
  • Take it as per the dose and duration prescribed by your doctor.
  • Monitor your blood sugar level regularly while you are taking this medicine.
  • It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal.
  • Always carry some sugary food or fruit juice with you in case you experience hypoglycemic symptoms such as cold sweats, cool pale skin, tremor, and anxi... View More
  • Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms such as abdominal pain, loss of appetite, or yellowing o... View More
  • Inform your doctor if you notice weight gain, shortness of breath, irregular heartbeat, or any abnormal swelling.
descriptionBrief Description

Indication

Type 2 DM

Adult Dose

Oral Type 2 Diabetes The recommended starting dose of Rosiglitazone/Metformin is 2 mg/500 mg once or twice daily. HbA1c >11% or fasting plasma glu... View More

Child Dose

Safety and efficacy not established

Renal Dose

Renal impairment Obtain eGFR before starting metformin eGFR <30 mL/min/1.73 m²: Contraindicated eGFR 30-45 mL/min/1.73 m²: Not recommended to initiat... View More

Contraindication

It is contraindicated in patients with renal disease or renal dysfunction (e.g., as suggested by serum creatinine levels .1.5 mg/dl (males), 1.4 mg/dl (... View More

Mode of Action

Rosiglitazone: Lowers glucose by improving target cell response to insulin without increasing pancreatic cell secretion; activates nuclear peroxisome pr... View More

Precaution

Rosiglitazone: should not be used in patients with type 1 diabetes. This should be used with caution in patients with edema. Dose-related weight gain wa... View More

Side Effect

>10% Edema (6% to 25% ),Upper respiratory infections (16-20%),Diarrhea (12.7% to 14%),Hypoglycemia (12% ) 1-10% Anemia (4% to 7%),Fatigue (6%),Head... View More

Interaction

Additive effect w/ sulfonylureas. Thiazide diuretics, corticosteroids, phenothiazines, OC, sympathomimetics, niacin, Ca channel blockers and isoniazid m... View More

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descriptionDisclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More