Actonel5mg

Indication

Paget's disease of bone, postmenopausal or corticosteroid-induced osteoporosis, increase bone mass in men with osteoporosis

Administration

Immediate release Take at least 30 minutes with 6-8 oz water before first food or drink of day Swallow with plain water only, not coffee or ... View More

Adult Dose

Oral Paget's disease of bone Adult: 30 mg once daily for 2 mth, may repeat if necessary after 2 mth interval. Treatment and prophylaxis of postmeno... View More

Renal Dose

Renal impairment: CrCl (ml/min) <30 Avoid use.

Contraindication

Hypocalcaemia, abnormalities of the oesophagus which may delay emptying (e.g. stricture or achalasia), inability to stand or sit upright for at least 30... View More

Mode of Action

Risedronic acid inhibits bone resorption by inhibiting osteoclasts. It also prevents formation and dissolution of hydroxyapatite crystals, and therefore... View More

Precaution

Correct hypocalcaemia and evaluate sex steroid hormonal status prior to therapy. Mild to moderate renal impairment. Pregnancy. Patient Counselling Ensur... View More

Side Effect

Arthralgia, back pain, GI disturbances (e.g. abdominal pain, dyspepsia), hypersensitivity reactions (e.g. angioedema, rash, bullous skin reactions), Ste... View More

Interaction

Co-admin with calcium, antacids or oral medications containing divalent cations may affect the absorption of risedronate. May have additive calcium lowe... View More