Introduction
Biotrim DS is a combination medicine that is used to treat various types of bacterial infections such as pneumonia, bronchitis, infections of urinary tr... View More
Uses of Biotrim DS
Side effects of Biotrim DS
How to use Biotrim DS
Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and ta... View More
How Biotrim DS works
Biotrim DS is a combination of two antibiotics: Sulfamethoxazole and Trimethoprim. These antibiotics work by preventing the bacteria from producing foli... View More
Indication
Upper and lower respiratory tract infections, Gastrointestinal tract infections, Renal and urinary tract infections, Skin and wound infections, Septicae... View More
Adult Dose
Oral Acute exacerbations of chronic bronchitis ; Acute otitis media; Urinary tract infections, GI infections; Resp and urinary tract infections; Suscep... View More
Child Dose
Child: Oral 8–10 mg TMP/kg/day q12h 2 mg TMP/kg/day for UTI prophylaxis q24h 15–20 mg TMP/kg/day for Pneumocystis (carinii) jiroveci pneumonia ... View More
Renal Dose
Renal impairment: CrCl (ml/min) Dosage Recommendation <15 Not recommended. 15-30 Half the standard dose.
Contraindication
Known hypersensitivity to trimethoprim or sulfonamides; severe hepatic failure or marked liver parenchymal damage, jaundice; serious haematological diso... View More
Mode of Action
Co-trimoxazole exhibits the synergistic actions of its components (sulfamethoxazole and trimethoprim) by 10-fold. Sulfamethoxazole inhibits dihydrofolic... View More
Precaution
Patient w/ severe allergy, bronchial asthma, thyroid dysfunction. Renal and mild to moderate hepatic impairment. Lactation. Patient Counselling May impa... View More
Side Effect
Allergic myocarditis, erythema multiforme, exfoliative dermatitis, angioedema, drug fever, chills, Henoch-Schoenlein purpura, serum sickness-like syndro... View More
Interaction
Reduced ciclosporin concentrations in blood when used concurrently. Increases toxicity of methotrexate. Inhibits phenytoin clearance. Potentiates warfar... View More
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The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More