Lastet100mg/5ml
Injection
Additional Offers
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| Alcohol | CONSULT YOUR DOCTOR It is not known whether it is safe to consume alcohol with Lastet. Please consult your doctor. |
| Pregnancy | CONSULT YOUR DOCTOR Lastet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in so... View More |
| Breastfeeding | UNSAFE Lastet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby. |
| Driving | SAFE Lastet does not usually affect your ability to drive. |
| Kidney | CAUTION Lastet should be used with caution in patients with kidney disease. Dose adjustment of Lastet may be needed. Please consult your doctor.
Use of Lastet i... View More |
| Liver | CAUTION Lastet should be used with caution in patients with liver disease. Dose adjustment of Lastet may be needed. Please consult your doctor.
Use of Lastet is... View More |
Introduction
Lastet is used to treat different cancers of lung, and testicles. It is also sometimes used to treat some other kinds of cancer in both men and women. I... View More
Uses of Lastet
- Small cell lung cancer
- Testicular cancer
Side effects of Lastet
- Anemia (low number of red blood cells)
- Decreased blood cells (red cells, white cells, and platelets)
- Decreased white blood cell count
- Diarrhea
- Hair loss
- Liver damage
- Low blood platelets
- Nausea
- Rash
- Stomatitis (Inflammation of the mouth)
- Vomiting
How to use Lastet
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Lastet works
Lastet is an anti-cancer medication. It works by suppressing the activity of an enzyme (topoisomerase II) involved in DNA multiplication of the cancer c... View More
Indication
Lung cancer, Testicular cancer
Adult Dose
Intravenous Testicular Cancer 50-100 mg/m²/day IV on days 1-5, OR 100 mg/m²/day IV on days 1, 3, 5 Repeat q3-4week Small-Cell Lung Cancer 35 mg... View More
Renal Dose
Renal Impairment CrCl >50 mL/min: Dose adjustment not necessary CrCl 15-50 mL/min: 75% of regular dose CrCl < 15 mL/min: Not studied; consider furthe... View More
Contraindication
Hypersensitivity, pregnancy, lactation.
Mode of Action
Etoposide is a derivative of podophyllotoxin that inhibits DNA synthesis resulting in the arrest of the cell cycle. At low doses, it inhibits cells from... View More
Precaution
Skin reactions may occur with accidental exposure; renal or hepatic disease. Periodic CBCs should be done before, during and after therapy. Increased ri... View More
Side Effect
>10% Leukopenia (60-91%),Nausea and Vomiting (30-40%),Thrombocytopenia (28-41%),Alopecia (20-90%),Anorexia (13%),Diarrhea (13%),Leukopenia (60-91%),Ane... View More
Pregnancy Category Note
Pregnancy: Based on animal data and its mechanism of action, etoposide can cause fetal harm when administered to a pregnant woman; etoposide, the active... View More
Interaction
Synergism with other cytotoxic drugs. Caution when admin with drugs that inhibit phosphatase activity. Cyclosporin A may reduce the clearance of etoposi... View More
Alternative brand for Lastet
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More