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Somatec Pharmaceuticals Ltd.
Generic: Sodium Valproate (valproic acid)
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descriptionSafety Advices
It is unsafe to consume alcohol with Valpro.
Valpro is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in so... View More
Valpro is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not har... View More
Valpro may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Valpro is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Valpro may not be needed in thes... View More
Valpro should be used with caution in patients with liver disease. Dose adjustment of Valpro may be needed. Please consult your doctor. Use of Valpro is... View More
descriptionMedical Overview


Valpro is a combination of two medicines used to treat epilepsy, a neurological disorder in which there are recurrent episodes of seizures or fits. It c... View More

Uses of Valpro

  • Epilepsy

Side effects of Valpro

  • Nausea
  • Vomiting
  • Weight gain
  • Loss of appetite
  • Gum swelling
  • Headache
  • Sleepiness
  • Tremor
  • Hair loss
  • Liver injury

How to use Valpro

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Valpro is to be taken with... View More

How Valpro works

Valpro is a combination of two antiepileptic medicines: Sodium Valproate and Valproic Acid. They work together to control seizures or fits by decreasing... View More

quick tipsQuick Tips
  • You have been prescribed Encorate Chrono 500 Tablet CR for treatment and prevention of seizures.
  • Take it at the same time every day to maintain consistent levels in your body.
  • Do not drive or do anything that requires mental focus until you know how Encorate Chrono 500 Tablet CR affects you.
  • Avoid consuming alcohol when taking Encorate Chrono 500 Tablet CR, as it may cause excessive sleepiness or drowsiness.
  • Monitor your weight during the treatment as Encorate Chrono 500 Tablet CR can cause weight gain.
  • Your doctor may monitor Encorate Chrono 500 Tablet CR level, blood counts and liver function regularly throughout your treatment. Inform your doctor if ... View More
  • Do not take Encorate Chrono 500 Tablet CR if you are pregnant or planning to conceive or breastfeeding.
  • Do not stop taking the medication suddenly without talking to your doctor as it may increase the seizure frequency.
descriptionBrief Description


Epilepsy, e.g. Partial seizures, Absence seizures (petit mal), Generalized tonic-clonic seizures (grand mal), Myoclonic seizures, Atonic seizures, Mixed... View More

Adult Dose

Oral Complex Partial Seizures Indicated as monotherapy and adjunctive therapy for complex partial seizures that occur either in isolation or in associ... View More

Child Dose

<10 years: Safety and efficacy not established Complex Partial Seizures Indicated as monotherapy and adjunctive therapy for complex partial seizures... View More

Renal Dose

Renal impairment No adjustment necessary


Preexisting or family history of hepatic dysfunction, active liver disease, porphyria; mitochondrial and urea cycle disorders. Hepatic impairment. Pregn... View More

Mode of Action

Valproate is a generic term used to describe valproic acid, its salts and derivatives. It is available in various forms including the sodium salts (valp... View More


Increased risk of hepatotoxicity in childn <2 yr, congenital metabolic disorders, organic brain disease or severe seizure disorders. HIV or cytomegalovi... View More

Side Effect

>10% Nausea (31%),Headache (<31%),Increased bleeding time (26-30%),Thrombocytopenia (26-30%),Tremor (25%),Alopecia (<24%),Asthenia (16-20%),Infection (... View More


Increased risk of toxicity w/ bupropion. Increased risk of convulsions w/ mefloquine. Increased risk of carnitine deficiency w/ pivmecillinam and pivamp... View More

Alternative brand for Valpro
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The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More

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