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Ranozex 500500mg

Tablet
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Sun Pharmaceutical (Bangladesh) Ltd.
Generic: Ranolazine
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148.80
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descriptionSafety Advices
AlcoholAlcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Ranozex 500. Please consult your doctor.
PregnancyPregnancy
CONSULT YOUR DOCTOR
Ranozex 500 may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the develo... View More
BreastfeedingBreastfeeding
CONSULT YOUR DOCTOR
Ranozex 500 is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
DrivingDriving
CONSULT YOUR DOCTOR
It is not known whether Ranozex 500 alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and... View More
KidneyKidney
CAUTION
Ranozex 500 should be used with caution in patients with kidney disease. Dose adjustment of Ranozex 500 may be needed. Please consult your doctor. Use o... View More
LiverLiver
CAUTION
Ranozex 500 should be used with caution in patients with liver disease. Dose adjustment of Ranozex 500 may be needed. Please consult your doctor. Use of... View More
descriptionMedical Overview

Introduction

Ranozex 500 is a medicine used for the management of angina (heart-related chest pain). It helps to prevent new attacks of angina, but it does not stop ... View More

Uses of Ranozex 500

  • Angina (heart-related chest pain)

Side effects of Ranozex 500

Common
  • Nausea
  • Vomiting
  • Headache
  • Dizziness
  • Constipation
  • Weakness

How to use Ranozex 500

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Ranozex 500 is to be taken... View More

How Ranozex 500 works

Ranozex 500 is an anti-anginal medication. It works by decreasing the oxygen requirement of the heart by relaxing heart muscle.

What if you forget to take Ranozex 500?

If you miss a dose of Ranozex 500, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to yo... View More

quick tipsQuick Tips
  • It should be taken with food to avoid stomach upset.
  • It improves HbA1c and blood sugar levels in diabetes patients.
  • It may cause dizziness or sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
  • Notify your doctor if you are taking any other medications along with Ranozex Tablet ER
  • It may produce changes in the ECG (QTc interval prolongation). It is recommended to get an ECG done within 1 to 2 weeks of starting the medication.
descriptionBrief Description

Indication

Chronic angina

Administration

May be taken with or without food.

Adult Dose

Oral Chronic angina 500 mg PO BID initially; may increase to 1,000 mg PO BID, if needed Hepatic Impairment: Mild: Dose titration needed. Moderate t... View More

Renal Dose

Renal Impairment Mild to moderate (CrCl 30-80 mL/min): Dose titration needed. Severe (CrCl <30 mL/min): Contraindicated.

Contraindication

Taking strong inhibitors of CYP3A (e.g., ketoconazole, clarithromycin, nelfinavir) Taking inducers of CYP3A (e.g., phenobarbital, rifampicin)Significant... View More

Mode of Action

Ranolazine exert its antianginal and anti-ischaemic effects through concentration-, voltage-, and frequency-dependent inhibition of the late Na current ... View More

Precaution

Heart rhythm problems (e.g., bradycardia, QT prolongation, ventricular tachycardia), liver problems, certain uncorrected mineral imbalances (low potassi... View More

Side Effect

>10% Dizziness (5-13%) 1-10% Nausea (4-9%),Constipation (5-8%),Headache (3-6%),Syncope (3%) Frequency Not Defined Palpitations,Bradycardia,Peri... View More

Interaction

Increased plasma levels w/ moderate CYP3A4 inhibitors (e.g. diltiazem, fluconazole, erythromycin), P-glycoprotein inhibitors (e.g. verapamil, ciclospori... View More

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descriptionDisclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More