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Square Pharmaceuticals PLC.
Generic: Topiramate
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descriptionSafety Advices
It is unsafe to consume alcohol with Piramed.
Piramed is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in s... View More
Piramed is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Piramed may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Piramed should be used with caution in patients with kidney disease. Dose adjustment of Piramed may be needed. Please consult your doctor.
Piramed should be used with caution in patients with liver disease. Dose adjustment of Piramed may be needed. Please consult your doctor.
descriptionMedical Overview


Piramed is a medicine used to treat epilepsy (seizures) and to prevent migraines. It is also used in the treatment of Lennox-Gastaut syndrome (a rare, b... View More

Uses of Piramed

  • Epilepsy/Seizures
  • Prevention of migraine
  • Lennox–Gastaut syndrome

Side effects of Piramed

  • Abdominal pain
  • Diarrhea
  • Dizziness
  • Fatigue
  • Fever
  • Loss of appetite
  • Memory impairment
  • Nausea
  • Nervousness
  • Numbness
  • Psychomotor impairment
  • Sleepiness
  • Speech disorder
  • Taste change
  • Upper respiratory tract infection
  • Visual impairment
  • Weight loss

How to use Piramed

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Piramed may be taken with ... View More

How Piramed works

Piramed is an antiepileptic medication. It controls seizures or fits by decreasing the abnormal and excessive activity of the nerve cells in the brain.

What if you forget to take Piramed?

If you miss a dose of Piramed, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your r... View More

quick tipsQuick Tips
  • Take your medication regularly as directed by your doctor as missing doses can trigger seizures.
  • Do not change the brand of your medicine and make sure that you have sufficient amount of medicine present with you.
  • Some healthy tips to prevent seizures:
  • It may cause dizziness and sleepiness. Do not drive or do anything that requires mental focus until you know how it affects you.
  • Keep yourself hydrated by drinking plenty of fluids throughout the day while taking Piramed. This can reduce the risk of kidney stones.
  • Monitor your weight during treatment with this medicine as it can cause weight gain.
  • Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts.
  • Do not stop taking the medication suddenly without talking to your doctor as it may increase the seizure frequency.
descriptionBrief Description


Epilepsy, Migraine prophylaxis, Seizures associated w/ Lennox-gastaut syndrome


May be taken with or without food.

Adult Dose

Oral Partial-Onset or Primary Generalized Tonic-Clonic Seizures Monotherapy Adult: 25 mg PO q12hr initially; may increase by 50 mg/day at weekly inte... View More

Child Dose

Oral Partial-Onset or Primary Generalized Tonic-Clonic Seizures Monotherapy <2 years: Safety and efficacy not established 2 to <10 years: 25 mg P... View More

Renal Dose

Renal impairment: Moderate to severe: Doses should be halved. Haemodialysis: supplemental dose equal to about ½ of the daily dose should be given in div... View More


Contraindicated in persons showing hypersensitivity to any component of this preparation.

Mode of Action

Topiramate is a sulfamate-substituted monosaccharide with precise mechanism of action unknown. It may be due to various mechanisms e.g. blocking of volt... View More


Renal or hepatic impairment, pregnancy, lactation. May impair ability to drive or operate machinery. Maintain adequate hydration to reduce the risk of ... View More

Side Effect

>10% Decrease in serum bicarbonate (7-67%),Dizziness (4-29%),Fatigue (9-16%),Ataxia (6-16%),Nervousness (9-18%),Paresthesia (1-11%),Psychomotor slowing... View More


Coadmin with antiepileptic drugs e.g. phenytoin, carbamazepine, phenobarbital decreases plasma concentration of topiramate. Possible increase in phenyto... View More


The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More

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