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Siglimet XR 50/10001000mg+50mg

Tablet
rx_reqRequire Prescription
Square Pharmaceuticals Ltd.
Generic: Metformin Hydrochloride + Sitagliptin
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97.20
MRP
108.00
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descriptionSafety Advices
AlcoholAlcohol
UNSAFE
It is unsafe to consume alcohol with Siglimet XR 50/1000.
PregnancyPregnancy
SAFE IF PRESCRIBED
Siglimet XR 50/1000 is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; ho... View More
BreastfeedingBreastfeeding
SAFE IF PRESCRIBED
Siglimet XR 50/1000 is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to t... View More
DrivingDriving
CAUTION
Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.
KidneyKidney
CAUTION
Siglimet XR 50/1000 should be used with caution in patients with kidney disease. Dose adjustment of Siglimet XR 50/1000 may be needed. Please consult yo... View More
LiverLiver
SAFE IF PRESCRIBED
Siglimet XR 50/1000 is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Siglimet XR 50/1000 ... View More
descriptionMedical Overview

Introduction

Siglimet XR 50/1000 is a combination of two medicines that control high blood sugar levels in people with type 2 diabetes mellitus. This helps prevent s... View More

Uses of Siglimet XR 50/1000

  • Type 2 diabetes mellitus

Side effects of Siglimet XR 50/1000

Common
  • Diarrhea
  • Nausea
  • Vomiting
  • Upset stomach
  • Headache
  • Nasal congestion (stuffy nose)
  • Sore throat
  • Respiratory tract infection
  • Hypoglycaemia (low blood sugar level) in combination with insulin or sulphonylurea

How to use Siglimet XR 50/1000

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Siglimet XR 50/1000 is to ... View More

How Siglimet XR 50/1000 works

Siglimet XR 50/1000 is a combination of two antidiabetic medicines: Sitagliptin and Metformin. They help your pancreas produce more insulin, facilitate ... View More

quick tipsQuick Tips
  • Take it with food to lower your chance of having an upset stomach.
  • Chances of weight gain and low blood sugar are lesser as compared to other diabetes medicines.
  • Inform your doctor about your diabetes treatment if you are due to have surgery under a general anaesthetic.
  • Tell your doctor immediately if you experience any deep or rapid breathing, persistent nausea, vomiting, and stomach pain as Janumet XR CP Tablet may ca... View More
descriptionBrief Description

Indication

Type 2 DM

Administration

Should be taken with food.

Adult Dose

Oral Type 2 DM The recommended starting dose in patients not currently treated with Metformin Initially 50 mg/500 mg bd. The starting dose in pat... View More

Child Dose

<18 years: Safety and efficacy not established

Renal Dose

Renal impairment Obtain eGFR before starting metformin eGFR <30 mL/min/1.73 m²: Contraindicated eGFR 30-45 mL/min/1.73 m²: Not recommended to initiat... View More

Contraindication

Renal dysfunction, e.g., serum creatinine >1.5 mg/dL [males], >1.4 mg/dL [females] or abnormal creatinine clearance. Metabolic acidosis, including dia... View More

Mode of Action

Sitagliptin: Dipeptidyl peptidase 4 (DPP-4) inhibitor, thereby increasing and prolonging incretin hormone activity which are inactivated by DPP-4 enzyme... View More

Precaution

Not for use in type 1 DM or treatment of ketoacidosis. Discontinue use if pancreatitis is suspected. Renal & hepatic impairment. Sulfonylurea- or insuli... View More

Side Effect

1-10% Abdominal pain (2.2%),Diarrhea (2.4%),Hypoglycemia (2.1%),Nausea (1.3%),Vomiting (1.1%) Frequency Not Defined Exfoliative disorder of skin of... View More

Interaction

Additive effect w/ sulfonylureas. Thiazide diuretics, corticosteroids, phenothiazines, OC, sympathomimetics, niacin, Ca channel blockers and isoniazid m... View More

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descriptionDisclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More