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Cyphos -1gm1000mg/vial

Injection
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Drug International Ltd.
Generic: Cyclophosphamide
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552.00
MRP
600.00
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descriptionSafety Advices
AlcoholAlcohol
UNSAFE
It is unsafe to consume alcohol with Cyphos -1gm.
PregnancyPregnancy
CONSULT YOUR DOCTOR
Cyphos -1gm is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it ... View More
BreastfeedingBreastfeeding
UNSAFE
Cyphos -1gm is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
DrivingDriving
UNSAFE
Cyphos -1gm may cause side effects which could affect your ability to drive. Cyphos -1gm may cause undesirable effects (e.g., dizziness, blurred vision,... View More
KidneyKidney
CAUTION
Cyphos -1gm should be used with caution in patients with severe kidney disease. Dose adjustment of Cyphos -1gm may be needed. Please consult your doctor... View More
LiverLiver
CAUTION
Cyphos -1gm should be used with caution in patients with liver disease. Dose adjustment of Cyphos -1gm may be needed. Please consult your doctor.
descriptionMedical Overview

Introduction

Cyphos -1gm is used in the treatment of different kinds of cancers. It is also used to treat kidney disease known as nephrotic syndrome in children afte... View More

Uses of Cyphos -1gm

  • Cancer
  • Nephrotic syndrome

Side effects of Cyphos -1gm

Common
  • Vomiting
  • Nausea
  • Hair loss
  • Fever
  • Blood in urine
  • Diarrhea
  • Decreased white blood cell count (neutrophils)

How to use Cyphos -1gm

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Cyphos -1gm is to be taken... View More

How Cyphos -1gm works

Cyphos -1gm is an anti-cancer medication. It is an alkylating agent which works by damaging the genetic material (DNA and RNA) of the cancer cells, ther... View More

quick tipsQuick Tips
  • Cyphos -1gm helps in the treatment of cancer.
  • Drink plenty of fluids or urinate frequently to prevent urinary problems while taking this medication.
  • Take it with food if you experience irritation of the stomach, preferably in the morning.
  • Your doctor may get regular blood tests to monitor your blood counts while on treatment with this medication.
  • You are more likely to get sick or heal slower while taking this medication. Talk to your doctor before getting any vaccines.
  • Contact your doctor immediately if you experience difficulty in urinating or blood in urine while on treatment with this medication.
  • Do not take Cyphos -1gm if you are pregnant or breastfeeding.
  • Use effective contraception method to prevent pregnancy while taking this medicine.
descriptionBrief Description

Indication

Bone marrow transplantation, malignancies, lymphomas, brain cancer, leukemia, systemic lupus erythematosus, minimal change disease, severe rheumatoid ar... View More

Administration

Should be taken on an empty stomach. Preferably taken on an empty stomach, but may be taken w/ meals to minimise GI irritation. Ensure adequate fluid in... View More

Adult Dose

Malignant Diseases IV (intermittent therapy): 40-50 mg/kg (400-1800 mg/m²) divided over 2-5 days; may be repeated at intervals of 2-4 weeks IV (cont... View More

Child Dose

Malignant Diseases IV (intermittent therapy): 40-50 mg/kg (400-1800 mg/m²) divided over 2-5 days; may be repeated at intervals of 2-4 weeks IV (cont... View More

Contraindication

Bladder haemorrhage. Patients with bone-marrow aplasia, acute infection, drug- or radiation-induced urothelial toxicity. Porphyria. Pregnancy and lactat... View More

Mode of Action

Cyclophosphamide is a prodrug which is converted in the body to the active metabolites. It acts at any stage of the cell cycle but its main action is bl... View More

Precaution

Blood disorders. Elderly or debilitated patients. Diabetic patients. Renal or hepatic impairment or who have gone adrenaloctomy. Previous treatment with... View More

Side Effect

Alopecia, skin and nails hyperpigmentation, nausea and vomiting, mucositis, inappropriate antidiuretic hormone secretion, carbohydrate metabolism distur... View More

Pregnancy Category Note

Pregnancy Based on mechanism of action and published reports of effects in pregnant patients or animals, drug can cause fetal harm when administered to... View More

Interaction

Increased risk of cardiotoxicity w/ doxorubicin or other cardiotoxic drugs. May increase incidence of mucositis w/ protease inhibitors. May increase hae... View More

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descriptionDisclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More

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