Pemeta100mg/ml
Injection
Drug International Ltd.
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| Alcohol | SAFE Consuming alcohol with Pemeta does not cause any harmful side effects. |
| Pregnancy | CONSULT YOUR DOCTOR Pemeta is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in so... View More |
| Breastfeeding | CAUTION Pemeta should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eli... View More |
| Driving | UNSAFE Pemeta may cause side effects which could affect your ability to drive.
Pemeta may make you feel tired and this may affect your ability to drive. |
| Kidney | CAUTION Pemeta should be used with caution in patients with kidney disease. Dose adjustment of Pemeta may be needed. Please consult your doctor.
Use of Pemeta i... View More |
| Liver | SAFE IF PRESCRIBED Pemeta is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Pemeta may not be needed in these... View More |
Introduction
Pemeta is used in the treatment of non-small cell lung cancer and malignant pleural mesothelioma. Pemeta is given as an injection by a qualified medica... View More
Uses of Pemeta
- Non-small cell lung cancer
- Malignant pleural mesothelioma
Side effects of Pemeta
- Nausea
- Vomiting
- Sore throat
- Loss of appetite
- Stomatitis (Inflammation of the mouth)
- Hair loss
- Low blood platelets
- Rash
- Fatigue
- Anemia (low number of red blood cells)
- Diarrhea
- Decreased white blood cell count (neutrophils)
- Neuropathy
How to use Pemeta
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Pemeta works
Pemeta interferes with the growth of DNA and RNA of the cancer cells by substituting their building blocks. It prevents the cancer cells from growing an... View More
- Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine.
- Inform your doctor immediately if you notice any signs of infection such as fever, sore throat, rash or severe diarrhea.
Indication
Non-small cell lung cancer, Malignant pleural mesothelioma
Administration
IV Preparation Aseptically reconstitute with 20 mL of 0.9% NaCl (preservative free) to give a 25 mg/mL solution Gently swirl until completely dissolve... View More
Adult Dose
Intravenous Malignant Pleural Mesothelioma Indicated for mesothelioma in combination with cisplatin in patients whose disease is unresectable or are n... View More
Child Dose
Safety and efficacy not established
Renal Dose
Renal impairment: CrCl (ml/min) Dosage Recommendation <45 Usage is not recommended.
Contraindication
Hypersensitivity.
Mode of Action
Pemetrexed is a thymidylate synthase inhibitor. It works by inhibiting thymidylate synthase, dihydrofolate reductase, glycinamide ribonucleotide formylt... View More
Precaution
Monitor CBC, platelet counts, and CrCl for nadir and recovery before each cycle. Periodic hepatic monitoring Premedication with folate and vitamin B12 a... View More
Side Effect
>10% Nausea (84%),Fatigue (80%),Pulmonary dyspnea (66%),Neutropenia (58%),Vomiting (58%),Leukopenia (55%),Constipation (44%),Chest pain (40%),Anorexia ... View More
Interaction
High doses of NSAIDs and aspirin may reduce the elimination of pemetrexed; avoid usage 2 days (5 days for longer-acting NSAIDs) before, during and 2 day... View More
Alternative brand for Pemeta
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More