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Larb Plus 12.5/10012.5mg+100mg

Tablet
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Opsonin Pharma Limited
Generic: Hydrochlorothiazide + Losartan Potassium
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descriptionSafety Advices
AlcoholAlcohol
UNSAFE
It is unsafe to consume alcohol with Larb Plus 12.5/100.
PregnancyPregnancy
CONSULT YOUR DOCTOR
Larb Plus 12.5/100 is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescr... View More
BreastfeedingBreastfeeding
SAFE IF PRESCRIBED
Larb Plus 12.5/100 is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to th... View More
DrivingDriving
UNSAFE
Larb Plus 12.5/100 may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
KidneyKidney
CAUTION
Larb Plus 12.5/100 should be used with caution in patients with severe kidney disease. Dose adjustment of Larb Plus 12.5/100 may be needed. Please consu... View More
LiverLiver
CAUTION
Larb Plus 12.5/100 should be used with caution in patients with liver disease. Dose adjustment of Larb Plus 12.5/100 may be needed. Please consult your ... View More
descriptionMedical Overview

Introduction

Larb Plus 12.5/100 is a combination of two medicines. It helps to control high blood pressure in different ways. If high blood pressure is not treated i... View More

Uses of Larb Plus 12.5/100

  • Hypertension (high blood pressure)

Side effects of Larb Plus 12.5/100

Common
  • Nausea
  • Taste change
  • Upset stomach
  • Diarrhea
  • Headache
  • Dizziness
  • Weakness
  • Decreased blood pressure
  • Increased blood uric acid
  • Increased blood lipid level
  • Glucose intolerance
  • Electrolyte imbalance

How to use Larb Plus 12.5/100

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Larb Plus 12.5/100 may be ... View More

How Larb Plus 12.5/100 works

Larb Plus 12.5/100 is a combination of two medicines: Losartan and Hydrochlorothiazide, which lowers the blood pressure effectively. Losartan is an angi... View More

quick tipsQuick Tips
  • You have been prescribed Larb Plus 12.5/100 for the treatment of high blood pressure.
  • It can be taken with or without food.
  • Larb Plus 12.5/100 may cause dehydration. Drink plenty of fluids and inform your doctor if you develop extreme thirst, very dry mouth or muscle weakness... View More
  • It may cause dizziness. Get up slowly when rising from a sitting or lying position.
  • Use of Larb Plus 12.5/100 during pregnancy or breastfeeding is unsafe.
  • It may also decrease the risk of stroke and heart attacks.
descriptionBrief Description

Indication

Hypertension, Stroke, risk reduction of hypertensive or LVH patients

Adult Dose

Hypertension Initial: 50 mg/12.5 mg PO qDay If dose titrated upward, do not to exceed final titration of 100 mg/25 mg PO qDay or 50 mg/12.5 mg PO q1... View More

Child Dose

Safety and efficacy not established

Renal Dose

Renal impairment CrCl <30 mL/min: Do not use thiazide-containing products; loop diuretic preferred CrCl >30 mL/min: No dosage adjustment required

Contraindication

Pregnancy, lactation; intravascular volume depletion.

Mode of Action

Hydrochlorothiazide increases renal excretion of sodium and chloride and reduces cardiac load. Losartan is an angiotensin II receptor (type AT1) antagon... View More

Precaution

Existing electrolyte disturbances; hepatic cirrhosis; severe hepatic failure; oedema; elderly (>75 yr); renal impairment; hepatic impairment; diabetes, ... View More

Side Effect

>10% Losartan Fatigue (14%),Hypoglycemia (14%),Chest pain (12%),Cough, incidence higher in previous cough related to ACE therapy (3-11%) 1-10% Los... View More

Interaction

Reduced excretion of lithium; effect of diuretic, natriuretic & other antihypertensive w/ NSAIDs including selective COX-2 inhibitors. Do not co-adminis... View More

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descriptionDisclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More