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Uparen 1515mg

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Renata Limited
Generic: Upadacitinib
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descriptionMedical Overview


Rheumatoid Arthritis

Adult Dose

Rheumatoid Arthritis Indicated for moderately to severely active rheumatoid arthritis in adults who have had an inadequate response or intolerance to m... View More

Renal Dose

Renal impairment Mild, moderate, or severe: No dose adjustment required ESRD: Not studied

Mode of Action

Janus kinase-1 (JAK1)-selective inhibitor; JAK1 is essential for signaling for certain cytokines to elicit signals from various interleukins, cardiotrop... View More


Malignancies reported; consider risks and benefits of treatment before initiating in patients with known malignancy, other than previously treated nonme... View More

Side Effect

>10% Upper respiratory tract infection (13.5%) 1-10% Nausea (3.5%) Neutropenia (1.1-2.4%) Lymphopenia (0.3-2.4%) Cough (2.2%) Elevated ... View More

Pregnancy Category Note

Pregnancy Limited human data on use in pregnant women are not sufficient to evaluate a drug-associated risk for major birth defects or miscarriage V... View More

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The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More