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Alimta500mg/Vial

Injection
rx_reqRequire Prescription
Eli Lilly and Company
Generic: Pemetrexed
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descriptionSafety Advices
AlcoholAlcohol
SAFE
Consuming alcohol with Alimta does not cause any harmful side effects.
PregnancyPregnancy
CONSULT YOUR DOCTOR
Alimta is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in so... View More
BreastfeedingBreastfeeding
CAUTION
Alimta should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eli... View More
DrivingDriving
UNSAFE
Alimta may cause side effects which could affect your ability to drive. Alimta may make you feel tired and this may affect your ability to drive.
KidneyKidney
CAUTION
Alimta should be used with caution in patients with kidney disease. Dose adjustment of Alimta may be needed. Please consult your doctor. Use of Alimta i... View More
LiverLiver
SAFE IF PRESCRIBED
Alimta is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Alimta may not be needed in these... View More
descriptionMedical Overview

Introduction

Alimta is used in the treatment of non-small cell lung cancer and malignant pleural mesothelioma. Alimta is given as an injection by a qualified medica... View More

Uses of Alimta

  • Non-small cell lung cancer
  • Malignant pleural mesothelioma

Side effects of Alimta

Common
  • Nausea
  • Vomiting
  • Sore throat
  • Loss of appetite
  • Stomatitis (Inflammation of the mouth)
  • Hair loss
  • Low blood platelets
  • Rash
  • Fatigue
  • Anemia (low number of red blood cells)
  • Diarrhea
  • Decreased white blood cell count (neutrophils)
  • Neuropathy

How to use Alimta

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Alimta works

Alimta interferes with the growth of DNA and RNA of the cancer cells by substituting their building blocks. It prevents the cancer cells from growing an... View More

quick tipsQuick Tips
  • Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine.
  • Inform your doctor immediately if you notice any signs of infection such as fever, sore throat, rash or severe diarrhea.
descriptionBrief Description

Indication

Non-small cell lung cancer, Malignant pleural mesothelioma

Administration

IV Preparation Aseptically reconstitute with 20 mL of 0.9% NaCl (preservative free) to give a 25 mg/mL solution Gently swirl until completely dissolve... View More

Adult Dose

Intravenous Malignant Pleural Mesothelioma Indicated for mesothelioma in combination with cisplatin in patients whose disease is unresectable or are n... View More

Child Dose

Safety and efficacy not established

Renal Dose

Renal impairment: CrCl (ml/min) Dosage Recommendation <45 Usage is not recommended.

Contraindication

Hypersensitivity.

Mode of Action

Pemetrexed is a thymidylate synthase inhibitor. It works by inhibiting thymidylate synthase, dihydrofolate reductase, glycinamide ribonucleotide formylt... View More

Precaution

Monitor CBC, platelet counts, and CrCl for nadir and recovery before each cycle. Periodic hepatic monitoring Premedication with folate and vitamin B12 a... View More

Side Effect

>10% Nausea (84%),Fatigue (80%),Pulmonary dyspnea (66%),Neutropenia (58%),Vomiting (58%),Leukopenia (55%),Constipation (44%),Chest pain (40%),Anorexia ... View More

Interaction

High doses of NSAIDs and aspirin may reduce the elimination of pemetrexed; avoid usage 2 days (5 days for longer-acting NSAIDs) before, during and 2 day... View More

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descriptionDisclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More

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