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Arofrez2.5mg

Tablet
rx_reqRequire Prescription
Healthcare Pharmaceuticals Ltd.
Generic: Letrozole
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Best Price
368.00
MRP
400.00
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descriptionSafety Advices
AlcoholAlcohol
SAFE
Consuming alcohol with Arofrez does not cause any harmful side effects.
PregnancyPregnancy
UNSAFE
Arofrez is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effe... View More
BreastfeedingBreastfeeding
UNSAFE
Arofrez is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
DrivingDriving
UNSAFE
Arofrez may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
KidneyKidney
SAFE IF PRESCRIBED
Arofrez is safe to use in patients with kidney disease. No dose adjustment of Arofrez is recommended. However, there is limited information on the use o... View More
LiverLiver
CAUTION
Arofrez should be used with caution in patients with liver disease. Dose adjustment of Arofrez may be needed. Please consult your doctor.
descriptionMedical Overview

Introduction

Arofrez is used alone or with other treatments, such as surgery or radiation, to treat early breast cancer in postmenopausal women. It can also be used ... View More

Uses of Arofrez

  • Breast cancer
  • Infertility due to anovulation

Side effects of Arofrez

Common
  • Fatigue
  • Hypercholesterolemia (high cholesterol)
  • Increased sweating

How to use Arofrez

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Arofrez may be taken with ... View More

How Arofrez works

Arofrez is an aromatase inhibitor. It works by decreasing the amount of estrogen (natural female hormone) produced in the body. This decrease in estroge... View More

What if you forget to take Arofrez?

If you miss a dose of Arofrez, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your r... View More

quick tipsQuick Tips
  • You have been prescribed Arofrez for the treatment of breast cancer or infertility due to anovulation.
  • It can be taken with or without food.
  • Do not drive or do anything requiring concentration until you know how Arofrez affects you.
  • It may cause increased sweating and hot flushes. Try to keep cool by wearing light and airy clothes.
  • Your doctor may monitor your cholesterol level and bone mineral density (BMD) regularly as Arofrez can alter their levels.
  • Do not take Arofrez if you are pregnant or breastfeeding
descriptionBrief Description

Indication

Breast cancer

Administration

May be taken with or without food.

Adult Dose

Oral Advanced or locally advanced breast cancer ; Adjuvant therapy for postmenopausal women with hormone receptor positive early breast cancer Adult: ... View More

Contraindication

Premenopausal women and children; hypersensitivity.

Mode of Action

Letrozole competitively binds to the heme group of aromatase, a cytochrome P450 enzyme which catalyzes conversion of androgen to oestrogen, leading to i... View More

Precaution

Severe renal impairment; severe hepatic impairment; osteoporosis. Caution when driving or operating machinery. Lactation: not known if excreted in br... View More

Side Effect

Hot flushes, arthralgia, nausea, vomiting, fatigue, dizziness, headache, dyspepsia, constipation, diarrhoea, anorexia, alopoecia, increased sweating, ra... View More

Interaction

Plasma levels reduced by tamoxifen.

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descriptionDisclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More