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Tagrix80mg

Tablet
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Beacon Pharmaceuticals Ltd.
Generic: Osimertinib
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2470.00
MRP
2600.00
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descriptionSafety Advices
AlcoholAlcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Tagrix. Please consult your doctor.
PregnancyPregnancy
CONSULT YOUR DOCTOR
Tagrix may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing ... View More
BreastfeedingBreastfeeding
CONSULT YOUR DOCTOR
Tagrix is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
DrivingDriving
SAFE
Tagrix does not usually affect your ability to drive.
KidneyKidney
SAFE IF PRESCRIBED
Tagrix is safe to use in patients with kidney disease. No dose adjustment of Tagrix is recommended.
LiverLiver
SAFE IF PRESCRIBED
Tagrix is safe to use in patients with liver disease. No dose adjustment of Tagrix is recommended.
descriptionMedical Overview

Introduction

Tagrix is a protein kinase inhibitors used in the treatment of non-small cell lung cancer. It is used in the treatment of adult patients who have certai... View More

Uses of Tagrix

  • Non-small cell lung cancer

Side effects of Tagrix

Common
  • Diarrhea
  • Loss of appetite
  • Rash
  • Stomatitis (Inflammation of the mouth)

How to use Tagrix

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Tagrix may be taken with o... View More

How Tagrix works

Tagrix is an anti-cancer medication. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps to stop o... View More

What if you forget to take Tagrix?

If you miss a dose of Tagrix, skip it and continue with your normal schedule. Do not double the dose.

quick tipsQuick Tips
  • Tagrix is used for the treatment of thyroid cancer.
  • Take it with or without food, preferably at the same time each day.
  • Diarrhea may occur as a side effect. Drink plenty of fluids and inform your doctor if it doesn't stop or if you find blood in your stools.
  • Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine and for a month after you stop taking it.
  • Monitor your blood pressure regularly while taking this medication. Inform your doctor if you notice symptoms of very high blood pressure such as severe... View More
  • It may cause serious bleeding problem. Inform your doctor if you get headaches, stomach pain or if you notice blood in your urine or stools.
  • Do not take this medicine if you are pregnant, planning to conceive or breastfeeding.
descriptionBrief Description

Indication

Non-small Cell Lung Cancer, Indicated for the treatment of patients with metastatic epidermal growth factor receptor (EGFR) T790M mutation-positive non... View More

Administration

May be taken with or without food: Take at the same time each day. Swallow whole, do not crush/split/chew. For patients w/ swallowing difficulties, ... View More

Adult Dose

Non-small Cell Lung Cancer 80 mg once daily. Hepatic impairment Mild (TB <ULN and AST 1-1.5 ULN, or TB 1-1.5 ULN and any AST): No dose adjustment r... View More

Child Dose

Safety and efficacy not established

Renal Dose

Renal impairment Mild-to-moderate (CrCl 30-89 mL/min): No dose adjustment required Severe or ESRD (CrCl <30 mL/min): There is no recommended dose

Contraindication

None

Mode of Action

Osimertinib is kinase inhibitor of the epidermal growth factor receptor (EGFR), which binds irreversibly to certain mutant forms of EGFR (T790M, L858R, ... View More

Precaution

Determine EGFR T790M mutation status prior to treatment. Interstitial lung disease (eg, pneumonitis). Avoid use in patients w/ congenital long QT syndro... View More

Side Effect

>10% Lymphopenia (63%),Thrombocytopenia (54%),Anemia (44%),Diarrhea (42%),Rash (41%),Neutropenia (33%),Dry skin (31%),Hyponatremia (26%),Nail toxicity ... View More

Interaction

Decreased exposure w/ strong CYP3A4 inducers (eg, phenytoin, rifampicin, carbamazepine, St. John's wort). May increase AUC & Cmax of rosuvastatin. May i... View More

descriptionDisclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More