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Square Pharmaceuticals PLC.
Generic: Estriol
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descriptionSafety Advices
No interaction found/established
Femastin may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developin... View More
Femastin is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
No interaction found/established
No interaction found/established
No interaction found/established
descriptionMedical Overview


Femastin is identical to a female hormone, estrogen. It is used to treat symptoms associated with menopause. This topical preparation helps to treat vag... View More

Uses of Femastin

Side effects of Femastin

  • Vaginal irritation

How to use Femastin

This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and ... View More

How Femastin works

Femastin contains oestrogen (female sex hormone). It works by delivering estrogens directly into the vagina to relieve vaginal symptoms of menopause suc... View More

quick tipsQuick Tips
  • It can be applied to the external vaginal area or inserted into the vagina using the applicator provided.
  • It does not expose the rest of your body to the medicine, thereby avoiding side effects that happen more often with pills.
  • Do not have sex right after using Femastin as some of the medicine can be absorbed into your partner's skin.
  • Inform your doctor if you experience any vaginal bleeding or spotting, abnormal vaginal discharge or vaginal discomfort while using this medicine.
  • Do not use Femastin if you are pregnant or breastfeeding, have a history of blood clots or heart diseases.
descriptionBrief Description


Infertility due to cervical hostility, Menopausal atrophic vaginitis, Menopausal hormone replacement therapy, Dyspareunia, Dryness and itching of vagina... View More


Tablet: May be taken with or without food.

Adult Dose

Oral Menopausal hormone replacement therapy Adult: 0.5-3 mg daily for 1 mth followed by 0.5-1 mg daily; or 0.25-2 mg daily in combination with other n... View More


• Pregnancy • Known, past or suspected breast cancer • Known or suspected oestrogen-dependent malignant tumours (e.g. endometrial cancer) • Undiagnosed ... View More

Mode of Action

Estriol is a naturally occurring oestrogen. It induces normalization of vag epithelium. It is claimed to have only a mild proliferative effect on the en... View More


In order to prevent endometrial stimulation, the daily dose should not exceed 8 mg nor should this maximum dose be used for longer than several weeks. A... View More

Side Effect

Breast tension or pain, nausea, spotting. Fluid retention, cervical hypersecretion.


Reduced efficacy may occur when used with activated charcoal, barbiturates, carbamazepine, griseofulvin, hydantoin and rifampicin. May possibly change e... View More


The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More

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