Introduction
Campto is used in the treatment of cancer of colon and rectum. It shows its working by stopping or slowing down the growth of cancer cells. Campto is g... View More
Uses of Campto
Side effects of Campto
How to use Campto
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Campto works
Campto is an anti-cancer medication. It works by suppressing the activity of an enzyme (topoisomerase I) involved in DNA multiplication of the cancer ce... View More
What if you forget to take Campto?
If you miss a dose of Campto, please consult your doctor.
Indication
Carcinoma of the colon or rectum
Administration
Reconstitution: Dilute in 5% dextrose injection (preferred) or 0.9% sodium chloride injection to a final concentration of 0.12-2.8 mg/ml.
Adult Dose
Intravenous Colorectal Cancer Indicated as first-line therapy (with 5-fluorouracil and leucovorin) for metastatic colorectal cancer (CRC); it is also ... View More
Child Dose
Not recommended
Contraindication
Patients with a known hypersensitivity to the drug or its excipients.
Mode of Action
Irinotecan, a derivative of camptothecin, works by inhibiting the enzyme topoisomerase I thereby interfering with the coiling and uncoiling of DNA durin... View More
Precaution
Early diarrhea is usually transient and infrequently severe. It may be accompanied by cholinergic symptoms of rhinitis, increased salivation, miosis, la... View More
Side Effect
>10% Anemia (>90%),Leukopenia (>90%),Neutropenia (>90%),Thrombocytopenia (>90%),Elevated bilirubin (88%),Diarrhea (85%),Nausea (79%),Asthenia (70%),Abd... View More
Interaction
Diuretics increase risks of dehydration secondary to vomiting/diarrhoea; prophylactic dexamethasone as an antiemetic may enhance lymphocytopenia; prochl... View More
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More