Introduction
Canarol 100 is used alone or in combination with other medicines to treat type 2 diabetes mellitus. It helps control the high blood sugar levels seen in... View More
Uses of Canarol 100
Side effects of Canarol 100
How to use Canarol 100
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Canarol 100 is to be taken... View More
How Canarol 100 works
Canarol 100 is an anti-diabetic medication. It works by removing excess sugar from your body through urine.
What if you forget to take Canarol 100?
If you miss a dose of Canarol 100, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to yo... View More
Indication
Type 2 diabetes mellitus
Adult Dose
Adults >18 years: Recommended Dose: 100 mg PO once daily taken before the first meal of the day May increase dose to 300 mg once daily in patients to... View More
Renal Dose
Renal impairment eGFR >60 mL/min/1.73 m²: No dosage adjustment required eGFR 45 to <60 mL/min/1.73 m²: Do not exceed 100 mg/day eGFR <4... View More
Contraindication
History of a serious hypersensitivity reaction and hypersensitivity to canagliflozin. Severe renal impairment (eGFR <30 mL/min/1.73 m2), end stage rena... View More
Mode of Action
Sodium-glucose co-transporter 2 SGLT-2 inhibition lowers the renal glucose threshold (ie, the plasma glucose concentration which exceed the maximum gluc... View More
Precaution
Causes intravascular volume contraction and symptomatic hypotension can occur, particularly if eGFR <60 mL/min/1.73 m²2, advance age, existing low systo... View More
Side Effect
>10% Female genital mycotic infections (10.4-11.4%) 1-10% Increased urination (4.6-5.3%),Male genital mycotic infections (3.7-4.2%),Vulvovaginal pr... View More
Pregnancy Category Note
Pregnancy Based on animal data showing adverse renal effects, not recommended during the second and third trimesters of pregnancy Data are limited i... View More
Interaction
Decreased efficacy w/ rifampicin. Increase AUC & Cmax of digoxin (not clinically meaningful).
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More